The NUCKS1 Polyclonal Antibody (CAB21091) is a valuable tool for researchers studying NUCKS1, a nuclear protein involved in DNA replication and repair processes. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been extensively validated for use in Western blot applications. By specifically targeting the NUCKS1 protein, researchers can accurately detect and analyze its expression in a variety of cell types, making it an essential tool for investigations in molecular biology and cancer research.
NUCKS1 is known for its role in maintaining genomic stability and regulating cell proliferation, making it a key player in processes related to cell growth and division. Dysregulation of NUCKS1 has been implicated in various diseases, including cancer and genetic disorders, highlighting its importance as a potential therapeutic target. By studying the functions of NUCKS1, researchers can gain valuable insights into the mechanisms underlying these conditions and develop targeted interventions to treat them effectively.
Product Name:
NUCKS1 Polyclonal Antibody
SKU:
CAB21091
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 100-200 of human NUCKS1 (NP_073568.2).
This gene encodes a nuclear protein that is highly conserved in vertebrates. The conserved regions of the protein contain several consensus phosphorylation sites for casein kinase II and cyclin-dependent kinases, two putative nuclear localization signals, and a basic DNA-binding domain. It is phosphorylated in vivo by Cdk1 during mitosis of the cell cycle.
Purification Method:
Affinity purification
Gene ID:
64710
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using NUCKS1 antibody (CAB21091) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
