Description
| Product Name: | MUSK Rabbit Polyclonal Antibody |
| SKU: | CAB2591 |
| Size: | 20uL, 100uL |
| Isotype: | IgG |
| Host Species: | Rabbit |
| Reactivity: | Mouse |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 424-783 of human MUSK (NP_001159752.1). |
| Sequence: | LTIT TLYC CRRR KQWK NKKR ESAA VTLT TLPS ELLL DRLH PNPM YQRM PLLL NPKL LSLE YPRN NIEY VRDI GEGA FGRV FQAR APGL LPYE PFTM VAVK MLKE EASA DMQA DFQR EAAL MAEF DNPN IVKL LGVC AVGK PMCL LFEY MAYG DLNE FLRS MSPH TVCS LSHS DLSM RAQV SSPG PPPL SCAE QLCI ARQV AAGM AYLS ERKF VHRD LATR NCLV GENM VVKI ADFG LSRN IYSA DYYK ANEN DAIP IRWM PPES IFYN RYTT ESDV WAYG VVLW EIFS YGLQ PYYG MAHE EVIY YVRD GNIL SCPE NCPV ELYN LMRL CWSK LPAD RPSF TSIH RILE RMCE RAEG TVSV |
| Tested Applications: | WB ELISA |
| Recommended Dilution: | WB,1:100 - 1:500 |
| Synonyms: | CMS9; FADS; FADS1; MUSK |
| Positive Sample: | Mouse skeletal muscle |
| Conjugate: | Unconjugated |
| Cellular Localization: | Cell junction, Single-pass type I membrane protein, postsynaptic cell membrane, synapse. |
| Calculated MW: | 97kDa |
| Observed MW: | 101kDa |
This gene encodes a muscle-specific tyrosine kinase receptor. The encoded protein may play a role in clustering of the acetylcholine receptor in the postsynaptic neuromuscular junction. Mutations in this gene have been associated with congenital myasthenic syndrome. Alternatively spliced transcript variants have been described.
| Purification Method: | Affinity purification |
| Gene ID: | 4593 |
| Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |
 | Western blot analysis of Mouse skeletal muscle, using MUSK antibody (CAB2591) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s. |
