![Anti-Mouse IFNgamma [XMG1.2] In Vivo Antibody - Low Endotoxin (IVMB0022)](https://cdn11.bigcommerce.com/s-d5atsu6k01/images/stencil/608x608/products/172933/172704/anti-mouse-ifng-xmg1.2-in-vivo-antibody-low-endotoxin__65665__82431.1750448950.jpg?c=1 "Anti-Mouse IFNgamma [XMG1.2] In Vivo Antibody - Low Endotoxin (IVMB0022)")
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Description
Anti-Mouse IFNγ [XMG1.2] In Vivo Antibody - Low Endotoxin
Introducing the Anti-Mouse IFN-γ [XMG1.2] In Vivo Antibody - Low Endotoxin from Assay Genie, a highly specific monoclonal antibody designed for in vivo applications. This antibody targets the interferon-gamma (IFN-γ), a key cytokine in immune response, making it an excellent tool for research in immunology, infectious disease, and related fields. With a rat IgG1 isotype, it ensures high purity and low endotoxin levels (<1.0 EU/mg), perfect for ELISA, flow cytometry, neutralization, and other assays. Available in various sizes, it is formulated in phosphate-buffered saline for stability and efficacy. Elevate your research with this reliable and versatile antibody.
IFN-γ is a dimerized soluble cytokine that is critical for innate and adaptive immunity against viral and intracellular bacterial infections and for tumor control. It is produced predominantly by natural killer (NK) and NKT cells as part of the innate immune response, and by CD4 Th1 and CD8 cytotoxic T lymphocyte (CTL) effector T-cells once antigen-specific immunity develops. It plays a significant role in immunomodulation, enhancing the antimicrobicidal activity of macrophages, the presentation of antigens, and the modulation of the immune response.
| Product Name: | Anti-Mouse IFNγ [XMG1.2] In Vivo Antibody - Low Endotoxin |
| Product Code: | IVMB0022 |
| Size: | 1mg, 5mg, 25mg, 50mg, 100mg |
| Clone: | XMG1.2 |
| Protein: | IFN-γ |
| Product Type: | Monoclonal Antibody |
| Synonyms: | Immune Interferon, Type II Interferon, T Cell Interferon, MAF, IFNG, IFG, IFI |
| Isotype: | Rat IgG1 κ |
| Reactivity: | Mouse |
| Immunogen: | Purified Recombinant Mouse IFN-γ (>98%) |
| Applications: | CyTOF®, ELISA Cap, ELISPOT, ICFC, IHC FF, N, WB |
| Formulation: | This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added. |
| Endotoxin Level: | < 1.0 EU/mg as determined by the LAL method |
| Purity: | ≥95% monomer by analytical SEC >95% by SDS Page |
| Preparation: | Functional grade preclinical antibodies are manufactured in an animal free facility using only In vitro protein free cell culture techniques and are purified by a multi-step process including the use of protein A or G to assure extremely low levels of endotoxins, leachable protein A or aggregates. |
| Storage and Handling: | Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles. |
| Applications: | CyTOF®, ELISA Cap, ELISPOT, ICFC, IHC FF, N, WB |
| Recommended Usage: | ELISA Cap XMG1.2 antibody is useful as a detection antibody for a sandwich ELISA with a concentration range of 0.5-2.0 µg/ml as recommended. WB The suggested concentration for this XMG1.2 antibody for use in western blotting is 1-10 µg/ml. |
| Reactivity: | Mouse |
| Host Species: | Rat |
| Specificity: | Rat Anti-Mouse Interferon Gamma (IFN-γ) (Clone XMG1.2) recognizes an epitope on Mouse IFN-γ. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype. |
| Immunogen: | Purified Recombinant Mouse IFN-γ (>98%) |
| Concentration: | ≥ 5.0 mg/ml |
| Endotoxin Level: | < 1.0 EU/mg as determined by the LAL method |
| Purity: | ≥95% monomer by analytical SEC >95% by SDS Page |
| Formulation: | This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added. |
| Preparation: | Functional grade preclinical antibodies are manufactured in an animal free facility using only In vitro protein free cell culture techniques and are purified by a multi-step process including the use of protein A or G to assure extremely low levels of endotoxins, leachable protein A or aggregates. |
| Storage and Handling: | Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles. |
Interferon-gamma (IFN-γ) or type II interferon is a dimerized soluble cytokine that is the only member of the type II class of interferons.1 It is a cytokine critical for innate and adaptive immunity against viral and intracellular bacterial infections and for tumor control. IFNG is produced predominantly by natural killer (NK) and natural killer T (NKT) cells as part of the innate immune response, and by CD4 and CD8 cytotoxic T lymphocyte (CTL) effector T cells once antigen-specific immunity develops.2 IFN-γ has antiviral, immunoregulatory, and anti-tumour properties.3
| Technical Datasheet: | View |
| Protein: | IFN-γ |
| Research Area: | Cell Biology, Immunology, Neuroinflammation, Neuroscience |
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