Description
Anti-Mouse CD120b (TNFR2) In Vivo Antibody - Ultra Low Endotoxin
Introducing the Anti-Mouse CD120b/TNFR2 In Vivo Antibody - Ultra Low Endotoxin from Assay Genie, a highly specific monoclonal antibody designed for in vivo applications. This antibody targets the CD120b/TNFR2 protein, which is essential in immune response signaling pathways, making it perfect for research in immunology, inflammation, and related fields. With a mouse IgG1 isotype, it ensures high purity and ultra-low endotoxin levels (<0.01 EU/μg), making it ideal for ELISA, flow cytometry, immunohistochemistry, and other assays. Available in various sizes, it is formulated in phosphate-buffered saline for enhanced stability and efficacy.
Boost your research outcomes with this reliable and versatile antibody. CD120b, also known as TNFR2 (Tumor Necrosis Factor Receptor 2), is a receptor that plays a critical role in the immune system by mediating the effects of TNF-alpha, including apoptosis, cell proliferation, and differentiation. This receptor is predominantly expressed on immune cells such as T cells, B cells, macrophages, and dendritic cells, and it is involved in regulating immune and inflammatory responses.
| Product Name: | Anti-Mouse CD120b (TNFR2) In Vivo Antibody - Ultra Low Endotoxin |
| Product Code: | IVMB0099 |
| Size: | 1mg, 5mg, 25mg, 50mg, 100mg |
| Clone: | TR75-54.7 |
| Protein: | TNFR2 |
| Product Type: | Monoclonal Antibody |
| Synonyms: | Tumor Necrosis Factor Receptor II, p75, CD120b, TBPII, TNF-R75, TNFBR, TNFR2, TNFR80, p75TNFR |
| Isotype: | Armenian Hamster IgG |
| Reactivity: | Mouse |
| Immunogen: | Purified Recombinant Mouse TNF R2 |
| Applications: | B, ELISA Cap, FC, IP, WB |
| Formulation: | This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added. |
| Endotoxin Level: | <0.5 EU/mg as determined by the LAL method |
| Purity: | ≥98% monomer by analytical SEC >95% by SDS Page |
| Preparation: | Functional grade preclinical antibodies are manufactured in an animal free facility using only In vitro protein free cell culture techniques and are purified by a multi-step process including the use of protein A or G to assure extremely low levels of endotoxins, leachable protein A or aggregates. |
| Storage and Handling: | Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles. |
| Applications: | B, ELISA Cap, FC, IP, WB |
| Recommended Usage: | FC The suggested concentration for clone TR75-54.7 antibody for staining cells in flow cytometry is ≤ .25 µg per 106 in a volume of 100 µl or 100µl of whole blood. Titration of the reagent is recommended for optimal performance for each application. |
| Reactivity: | Mouse |
| Host Species: | Armenian Hamster |
| Specificity: | Anti-Mouse CD120 recognizes Mouse CD120. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype. |
| Antigen Distribution: | Variety of cell types at low levels |
| Immunogen: | Purified Recombinant Mouse TNF R2 |
| Concentration: | ≥ 5.0 mg/ml |
| Endotoxin Level: | <0.5 EU/mg as determined by the LAL method |
| Purity: | ≥98% monomer by analytical SEC >95% by SDS Page |
| Formulation: | This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added. |
| Preparation: | Functional grade preclinical antibodies are manufactured in an animal free facility using only In vitro protein free cell culture techniques and are purified by a multi-step process including the use of protein A or G to assure extremely low levels of endotoxins, leachable protein A or aggregates. |
| Storage and Handling: | Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles. |
Tumor necrosis factor receptor II (TNF-RII) is present on most cell types1 and is considered to play a prominent role in stimulation by TNF-alpha. TNFRII proteins are expressed by hematopoietic cells including macrophages, neutrophils, lymphocytes, thymocytes and mast cells. It is expressed by a variety of other cell types including endothelial cells, cardiac myocytes and prostate cells.2
| Technical Datasheet: | View |
| Protein: | TNFR2 |
| Function: | Apoptosis, NF-κB activation, inflammation, tumor necrosis, cell differentiation |
| Ligand/Receptor: | TNF-α, LT-α (TNF-β) |
| Research Area: | Immunology, Innate Immunity |
| Armenian Hamster IgG Isotype Control | |
|---|---|
| Clone | PIP |
| Isotype | Armenian Hamster IgG1 |
| Endotoxin Level | Ultra Low Endotoxin |
