The Anti-HSD3B1 Antibody (CAB19266) is a reliable tool for studying HSD3B1, an enzyme involved in the biosynthesis of steroid hormones such as progesterone and testosterone. This antibody, produced through immunization of rabbits, exhibits high specificity and sensitivity towards human samples, making it suitable for use in Western blotting and immunohistochemistry applications.HSD3B1, also known as 3-beta-Hydroxysteroid Dehydrogenase Type 1, plays a crucial role in steroid hormone production and has been implicated in various hormone-related conditions such as adrenal hyperplasia and hormone-dependent cancers.
By targeting HSD3B1 with this antibody, researchers can investigate its expression levels and localization in different tissues, aiding in the understanding of steroid hormone biosynthesis pathways and their potential dysregulation in disease states.The Anti-HSD3B1 Antibody (CAB19266) offers a valuable tool for researchers in the fields of endocrinology, reproductive biology, and cancer research, providing insights into the role of HSD3B1 in hormone metabolism and its potential as a therapeutic target for hormonally-driven diseases.
Product Name:
HSD3B1 Rabbit Monoclonal Antibody
SKU:
CAB19266
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 250-350 of human HSD3B1 (P14060).
The protein encoded by this gene is an enzyme that catalyzes the oxidative conversion of delta-5-3-beta-hydroxysteroid precursors into delta-4-ketosteroids, which leads to the production of all classes of steroid hormones. The encoded protein also catalyzes the interconversion of 3-beta-hydroxy- and 3-keto-5-alpha-androstane steroids.
Purification Method:
Affinity purification
Gene ID:
3283
Clone Number:
ARC2437
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using HSD3B1 Rabbit mAb (CAB19266) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
