The Anti-HE4 (WFDC2) Antibody (CAB3276) from Assay Genie is a highly specific and sensitive tool for research involving the HE4 protein, also known as WFDC2. This antibody, raised in rabbits, is validated for use in various applications, including Western blot, immunohistochemistry, and ELISA.HE4 is a biomarker with emerging importance in cancer research, particularly in the detection and monitoring of ovarian cancer. The Anti-HE4 Antibody (CAB3276) binds specifically to the HE4 protein, enabling accurate detection and analysis in biological samples.
Its high reactivity with human samples makes it a valuable tool for studying the role of HE4 in cancer development and progression.The Anti-HE4 (WFDC2) Antibody (CAB3276) is a crucial asset for researchers investigating the potential of HE4 as a diagnostic and prognostic marker in cancer, as well as its potential role in other diseases and conditions. Its specificity and sensitivity make it an ideal choice for studies aiming to understand the function and implications of HE4 in human biology.
Product Name:
HE4/WFDC2 Rabbit Monoclonal Antibody
SKU:
CAB3276
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 45-124 of human HE4/WFDC2 (Q14508).
This gene encodes a protein that is a member of the WFDC domain family. The WFDC domain, or WAP Signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. This gene is expressed in pulmonary epithelial cells, and was also found to be expressed in some ovarian cancers. The encoded protein is a small secretory protein, which may be involved in sperm maturation.
Purification Method:
Affinity purification
Gene ID:
10406
Clone Number:
ARC1936
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using HE4/WFDC2 Rabbit mAb (CAB3276) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3min.
