The Gal3ST4 Polyclonal Antibody (CAB4979) is a valuable tool for researchers studying Gal3ST4, an enzyme involved in the biosynthesis of glycolipids and essential for cell-cell recognition and communication. Raised in rabbits, this antibody is highly specific for human samples and has been validated for use in various applications, including Western blotting.Gal3ST4 plays a crucial role in glycolipid metabolism and has been implicated in various biological processes, such as cell adhesion, signaling, and development. By targeting the Gal3ST4 protein, researchers can gain valuable insights into its functions and pathways, making it an ideal antibody for studies in glycobiology and cell biology.
Understanding the role of Gal3ST4 is essential for unraveling its significance in physiological and pathological conditions, including cancer, neurodegenerative diseases, and immune disorders. By investigating the expression and activity of Gal3ST4, researchers can uncover potential therapeutic targets and pathways for intervention in these diseases.
Product Name:
GAL3ST4 Rabbit Polyclonal Antibody
SKU:
CAB4979
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 137-486 of human GAL3ST4 (NP_078913.3).
Golgi apparatus, Golgi stack membrane, Single-pass type II membrane protein.
Calculated MW:
54kDa
Observed MW:
54kDa
This gene encodes a member of the galactose-3-O-sulfotransferase protein family. The product of this gene catalyzes sulfonation by transferring a sulfate to the C-3' position of galactose residues in O-linked glycoproteins. This enzyme is highly specific for core 1 structures, with asialofetuin, Gal-beta-1,3-GalNAc and Gal-beta-1,3 (GlcNAc-beta-1,6)GalNAc being good substrates.
Purification Method:
Affinity purification
Gene ID:
79690
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using GAL3ST4 antibody (CAB4979) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3s.
