The CTIP2/Bcl11b Polyclonal Antibody (CAB19804) is a valuable tool for researchers studying the CTIP2/Bcl11b protein, which plays a critical role in immune regulation and cell differentiation processes. The antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications.CTIP2/Bcl11b is a transcription factor that plays a key role in regulating gene expression in immune cells, specifically in T cell development and function. It is also implicated in cancer progression and neurodevelopmental disorders.
The use of this antibody allows for the detection and analysis of CTIP2/Bcl11b in various cell types, making it ideal for studies in immunology, cancer biology, and neuroscience.Understanding the function and regulation of CTIP2/Bcl11b is crucial for advancing research in areas such as immune response modulation, cancer therapy, and developmental biology. This antibody provides a reliable tool for researchers to further investigate the role of CTIP2/Bcl11b in these important biological processes.
Product Name:
CTIP2/BCL11B Rabbit Monoclonal Antibody
SKU:
CAB19804
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 450-550 of human CTIP2/BCL11B (Q9C0K0).
This gene encodes a C2H2-type zinc finger protein and is closely related to BCL11A, a gene whose translocation may be associated with B-cell malignancies. Although the specific function of this gene has not been determined, the encoded protein is known to be a transcriptional repressor, and is regulated by the NURD nucleosome remodeling and histone deacetylase complex. Four alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
64919
Clone Number:
ARC2329
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using CTIP2/BCL11B Rabbit mAb (CAB19804) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
