| UniProt Protein Function: | ALDOC: a member of the class I fructose-biphosphate aldolase gene family. Expressed specifically in the hippocampus and Purkinje cells of the brain, the encoded protein is a glycolytic enzyme that catalyzes the reversible aldol cleavage of fructose-1,6-biphosphate and fructose 1-phosphate to dihydroxyacetone phosphate and either glyceraldehyde-3-phosphate or glyceraldehyde, respectively. [provided by RefSeq, Jul 2008] |
| UniProt Protein Details: | Protein type:EC 4.1.2.13; Lyase; Carbohydrate Metabolism - glycolysis and gluconeogenesis; Carbohydrate Metabolism - pentose phosphate pathway; Carbohydrate Metabolism - fructose and mannose Chromosomal Location of Human Ortholog: 17cen-q12 Cellular Component: cytoskeleton; cytosol Molecular Function:cytoskeletal protein binding; fructose-bisphosphate aldolase activity; protein binding Biological Process: epithelial cell differentiation; fructose 1,6-bisphosphate metabolic process; fructose metabolic process; gluconeogenesis |
| NCBI Summary: | This gene encodes a member of the class I fructose-biphosphate aldolase gene family. Expressed specifically in the hippocampus and Purkinje cells of the brain, the encoded protein is a glycolytic enzyme that catalyzes the reversible aldol cleavage of fructose-1,6-biphosphate and fructose 1-phosphate to dihydroxyacetone phosphate and either glyceraldehyde-3-phosphate or glyceraldehyde, respectively. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P09972 |
| NCBI GenInfo Identifier: | 113613 |
| NCBI Gene ID: | 230 |
| NCBI Accession: | P09972.2 |
| UniProt Secondary Accession: | P09972,Q3SYL3, Q6FH94, Q6P0L5, B2R5R3, |
| UniProt Related Accession: | P09972 |
| Molecular Weight: | 39,456 Da |
| NCBI Full Name: | Fructose-bisphosphate aldolase C |
| NCBI Synonym Full Names: | aldolase, fructose-bisphosphate C |
| NCBI Official Symbol: | ALDOC |
| NCBI Official Synonym Symbols: | ALDC |
| NCBI Protein Information: | fructose-bisphosphate aldolase C |
| UniProt Protein Name: | Fructose-bisphosphate aldolase C |
| UniProt Synonym Protein Names: | Brain-type aldolase |
| Protein Family: | Fructose-bisphosphate aldolase |
| UniProt Gene Name: | ALDOC |
| UniProt Entry Name: | ALDOC_HUMAN |
