Description
| 抗体名: | ALDH9A1 Antibody (PACO48830) |
| 抗体コード: | PACO48830 |
| サイズ: | 50ug |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, IHC, IF |
| 推奨される希釈: | ELISA:1:2000-1:10000, IHC:1:20-1:200, IF:1:50-1:200 |
| 反応性: | Human |
| 免疫原: | Recombinant Human 4-trimethylaminobutyraldehyde dehydrogenase protein (12-144AA) |
| 憲法: | Liquid |
| ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| 精製方法: | >95%, Protein G purified |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human liver cancer using PACO48830 at dilution of 1:100. |
 | Immunofluorescent analysis of Hela cells using PACO48830 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
| バックグラウンド: | Converts gamma-trimethylaminobutyraldehyde into gamma-butyrobetaine. Catalyzes the irreversible oxidation of a broad range of aldehydes to the corresponding acid, in an NAD-dependent reaction. |
| シノニム: | 4-trimethylaminobutyraldehyde dehydrogenase (TMABADH) (EC 1.2.1.47) (Aldehyde dehydrogenase E3 isozyme) (Aldehyde dehydrogenase family 9 member A1) (EC 1.2.1.3) (Gamma-aminobutyraldehyde dehydrogenase) (EC 1.2.1.19) (R-aminobutyraldehyde dehydrogenase) [Cleaved into: 4-trimethylaminobutyraldehyde dehydrogenase, N-terminally processed], ALDH9A1, ALDH4 ALDH7 ALDH9 |
| UniProt Protein Function: | ALDH9A1: Converts gamma-trimethylaminobutyraldehyde into gamma- butyrobetaine. Catalyzes the irreversible oxidation of a broad range of aldehydes to the corresponding acids in an NAD-dependent reaction. Belongs to the aldehyde dehydrogenase family. |
| UniProt Protein Details: | Protein type:Other Amino Acids Metabolism - beta-alanine; Lipid Metabolism - fatty acid; Amino Acid Metabolism - lysine degradation; Amino Acid Metabolism - valine, leucine and isoleucine degradation; Secondary Metabolites Metabolism - limonene and pinene degradation; Carbohydrate Metabolism - ascorbate and aldarate; Oxidoreductase; Amino Acid Metabolism - tryptophan; EC 1.2.1.47; EC 1.2.1.3; Amino Acid Metabolism - arginine and proline; Carbohydrate Metabolism - butanoate; Lipid Metabolism - glycerolipid; Amino Acid Metabolism - histidine; Carbohydrate Metabolism - propanoate; Mitochondrial; Carbohydrate Metabolism - glycolysis and gluconeogenesis; Carbohydrate Metabolism - pyruvate Chromosomal Location of Human Ortholog: 1q23.1 Cellular Component: cytoplasm; cytosol Molecular Function:3-chloroallyl aldehyde dehydrogenase activity; 4-trimethylammoniobutyraldehyde dehydrogenase activity; aldehyde dehydrogenase (NAD) activity; aminobutyraldehyde dehydrogenase activity Biological Process: aldehyde metabolic process; carnitine biosynthetic process; hormone metabolic process; neurotransmitter biosynthetic process |
| NCBI Summary: | This protein belongs to the aldehyde dehydrogenase family of proteins. It has a high activity for oxidation of gamma-aminobutyraldehyde and other amino aldehydes. The enzyme catalyzes the dehydrogenation of gamma-aminobutyraldehyde to gamma-aminobutyric acid (GABA). This isozyme is a tetramer of identical 54-kD subunits. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P49189 |
| NCBI GenInfo Identifier: | 62511242 |
| NCBI Gene ID: | 223 |
| NCBI Accession: | P49189.3 |
| UniProt Secondary Accession: | P49189,Q5VV90, Q6LCL1, Q9NZT7, B2R6X1, B4DXY7, |
| UniProt Related Accession: | P49189 |
| Molecular Weight: | 46,455 Da |
| NCBI Full Name: | 4-trimethylaminobutyraldehyde dehydrogenase |
| NCBI Synonym Full Names: | aldehyde dehydrogenase 9 family member A1 |
| NCBI Official Symbol: | ALDH9A1 |
| NCBI Official Synonym Symbols: | E3; ALDH4; ALDH7; ALDH9; TMABADH |
| NCBI Protein Information: | 4-trimethylaminobutyraldehyde dehydrogenase |
| UniProt Protein Name: | 4-trimethylaminobutyraldehyde dehydrogenase |
| UniProt Synonym Protein Names: | Aldehyde dehydrogenase E3 isozyme; Aldehyde dehydrogenase family 9 member A1 (EC:1.2.1.3); Gamma-aminobutyraldehyde dehydrogenase (EC:1.2.1.19); R-aminobutyraldehyde dehydrogenase |
| Protein Family: | Aldehyde dehydrogenase family |
| UniProt Gene Name: | ALDH9A1 |
| UniProt Entry Name: | AL9A1_HUMAN |
