Description
| 抗体名: | ALDH3A1 Antibody |
| 抗体コード: | PACO01744 |
| サイズ: | 50ug |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, WB |
| 推奨される希釈: | WB:1:500-1:2000 |
| 反応性: | Human, Rat |
| 免疫原: | synthesized peptide derived from the Internal region of human ALDH3A1. |
| 憲法: | Liquid |
| ストレージバッファ: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| 精製方法: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
| シノニム: | ALDH3A1; ALDH3; Aldehyde dehydrogenase, dimeric NADP-preferring; ALDHIII; Aldehyde dehydrogenase 3; Aldehyde dehydrogenase family 3 member A1 |
| UniProt Protein Function: | ALDH3A1: ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. This protein preferentially oxidizes aromatic aldehyde substrates. It may play a role in the oxidation of toxic aldehydes. Belongs to the aldehyde dehydrogenase family. |
| UniProt Protein Details: | Protein type:Xenobiotic Metabolism - drug metabolism - cytochrome P450; Amino Acid Metabolism - phenylalanine; Carbohydrate Metabolism - glycolysis and gluconeogenesis; EC 1.2.1.5; Amino Acid Metabolism - histidine; Xenobiotic Metabolism - metabolism by cytochrome P450; Amino Acid Metabolism - tyrosine; Oxidoreductase Chromosomal Location of Human Ortholog: 17p11.2 Cellular Component: cytoplasm; cytosol; endoplasmic reticulum; extracellular space; intracellular membrane-bound organelle; nucleoplasm; plasma membrane Molecular Function:3-chloroallyl aldehyde dehydrogenase activity; alcohol dehydrogenase (NADP+) activity; aldehyde dehydrogenase (NAD) activity; aldehyde dehydrogenase [NAD(P)+] activity; benzaldehyde dehydrogenase (NAD+) activity; protein binding Biological Process: aldehyde metabolic process; xenobiotic metabolic process |
| NCBI Summary: | Aldehyde dehydrogenases oxidize various aldehydes to the corresponding acids. They are involved in the detoxification of alcohol-derived acetaldehyde and in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. The enzyme encoded by this gene forms a cytoplasmic homodimer that preferentially oxidizes aromatic and medium-chain (6 carbons or more) saturated and unsaturated aldehyde substrates. It is thought to promote resistance to UV and 4-hydroxy-2-nonenal-induced oxidative damage in the cornea. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Sep 2008] |
| UniProt Code: | P30838 |
| NCBI GenInfo Identifier: | 311033473 |
| NCBI Gene ID: | 218 |
| NCBI Accession: | P30838.3 |
| UniProt Secondary Accession: | P30838,Q9BT37, A8K828, |
| UniProt Related Accession: | P30838 |
| Molecular Weight: | 50,395 Da |
| NCBI Full Name: | Aldehyde dehydrogenase, dimeric NADP-preferring |
| NCBI Synonym Full Names: | aldehyde dehydrogenase 3 family member A1 |
| NCBI Official Symbol: | ALDH3A1 |
| NCBI Official Synonym Symbols: | ALDH3; ALDHIII |
| NCBI Protein Information: | aldehyde dehydrogenase, dimeric NADP-preferring |
| UniProt Protein Name: | Aldehyde dehydrogenase, dimeric NADP-preferring |
| UniProt Synonym Protein Names: | ALDHIII; Aldehyde dehydrogenase 3; Aldehyde dehydrogenase family 3 member A1 |
| Protein Family: | Aldehyde dehydrogenase |
| UniProt Gene Name: | ALDH3A1 |
| UniProt Entry Name: | AL3A1_HUMAN |
