Description
| 抗体名: | AIDA Antibody, Biotin conjugated (PACO63842) |
| 抗体コード: | PACO63842 |
| サイズ: | 50ul |
| 宿主種: | Rabbit |
| 申し込み: | ELISA |
| 推奨される希釈: | |
| 反応性: | Human |
| 免疫原: | Recombinant Human Axin interactor, dorsalization-associated protein (14-306AA) |
| 憲法: | Liquid |
| ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| 精製方法: | Antigen Affinity Purified |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Biotin |
| バックグラウンド: | Acts as a ventralizing factor during embryogenesis. Inhibits axin-mediated JNK activation by binding axin and disrupting axin homodimerization. This in turn antagonizes a Wnt/beta-catenin-independent dorsalization pathway activated by AXIN/JNK-signaling (By similarity). |
| シノニム: | Axin interactor, dorsalization-associated protein (Axin interaction partner and dorsalization antagonist), AIDA, C1orf80 |
| UniProt Protein Function: | AIDA: Acts as a ventralizing factor during embryogenesis. Inhibits axin-mediated JNK activation by binding axin and disrupting axin homodimerization. This in turn antagonizes a Wnt/beta-catenin-independent dorsalization pathway activated by AXIN/JNK-signaling. Belongs to the AIDA family. 3 isoforms of the human protein are produced by alternative splicing.Protein type: Cell development/differentiationChromosomal Location of Human Ortholog: 1q41Molecular Function: protein bindingBiological Process: dorsal/ventral pattern formation; negative regulation of JNK activity; negative regulation of JNK cascade; regulation of protein homodimerization activity |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q96BJ3 |
| NCBI GenInfo Identifier: | 74751770 |
| NCBI Gene ID: | 64853 |
| NCBI Accession: | Q96BJ3.1 |
| UniProt Secondary Accession: | Q96BJ3,Q49A81, Q5JRA4, Q658P1, Q9H9E8, A8K1F0 |
| UniProt Related Accession: | Q96BJ3 |
| Molecular Weight: | 25,914 Da |
| NCBI Full Name: | Axin interactor, dorsalization-associated protein |
| NCBI Synonym Full Names: | axin interactor, dorsalization associated |
| NCBI Official Symbol: | AIDA |
| NCBI Official Synonym Symbols: | C1orf80 |
| NCBI Protein Information: | axin interactor, dorsalization-associated protein |
| UniProt Protein Name: | Axin interactor, dorsalization-associated protein |
| UniProt Synonym Protein Names: | Axin interaction partner and dorsalization antagonist |
| Protein Family: | AIDA-I autotransporter |
| UniProt Gene Name: | AIDA |
| UniProt Entry Name: | AIDA_HUMAN |
