| NCBI Summary: | This gene encodes a member of the RGS (regulator of G protein signaling) family of proteins, which are defined by the presence of a RGS domain that confers the GTPase-activating activity of these proteins toward certain G alpha subunits. This protein also belongs to a subfamily of RGS proteins characterized by the presence of DEP and GGL domains, the latter a G beta 5-interacting domain. The RGS proteins negatively regulate G protein signaling, and may modulate neuronal, cardiovascular, lymphocytic activities, and cancer risk. Many alternatively spliced transcript variants encoding different isoforms with long or short N-terminal domains, complete or incomplete GGL domains, and distinct C-terminal domains, have been described for this gene, however, the full-length nature of some of these variants is not known.[provided by RefSeq, Mar 2011] |
| UniProt Code: | O43865 |
| NCBI GenInfo Identifier: | 109731743 |
| NCBI Gene ID: | 9628 |
| NCBI Accession: | BC113572 |
| UniProt Secondary Accession: | O43865,O75576, O75577, Q7Z4K3, Q7Z4K4, Q7Z4K5, Q7Z4K6 Q8TE13, Q8TE14, Q8TE15, C9JE95, F8W7W5, |
| UniProt Related Accession: | P49758 |
| Molecular Weight: | 53,319 Da |
| NCBI Full Name: | Homo sapiens regulator of G-protein signaling 6, mRNA |
| NCBI Synonym Full Names: | regulator of G-protein signaling 6 |
| NCBI Official Symbol: | RGS6 |
| NCBI Official Synonym Symbols: | GAP; S914; HA117 |
| NCBI Protein Information: | regulator of G-protein signaling 6 |
| UniProt Protein Name: | Putative adenosylhomocysteinase 2 |
| UniProt Synonym Protein Names: | DC-expressed AHCY-like molecule; IP(3)Rs binding protein released with IP(3); IRBIT; S-adenosyl-L-homocysteine hydrolase 2; S-adenosylhomocysteine hydrolase-like protein 1 |
| Protein Family: | Regulator of G-protein signaling |
| UniProt Gene Name: | AHCYL1 |
| UniProt Entry Name: | SAHH2_HUMAN |
