Description
| 抗体名: | ADI1 Antibody (PACO07401) |
| 抗体コード: | PACO07401 |
| サイズ: | 50ug |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, IHC |
| 推奨される希釈: | ELISA:1:10000-1:20000, IHC-p:1:50-1:300 |
| 反応性: | Human, Mouse, Rat |
| 免疫原: | Synthetic peptide from human protein at AA range: 71-120 |
| 憲法: | Liquid |
| ストレージバッファ: | PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol. |
| 精製方法: | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemical analysis of paraffin-embedded human-lung, antibody was diluted at 1:200. |
| シノニム: | 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase (EC 1.13.11.54) (Acireductone dioxygenase (Fe(2+)-requiring)) (ARD) (Fe-ARD) (Membrane-type 1 matrix metalloproteinase cytoplasmic tail-binding protein 1) (MTCBP-1) (Submergence-induced protein-like factor) (Sip-L) |
| UniProt Protein Function: | ADI1: Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene). Also down-regulates cell migration mediated by MMP14. Necessary for hepatitis C virus replication in an otherwise non-permissive cell line. Belongs to the acireductone dioxygenase (ARD) family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Amino Acid Metabolism - cysteine and methionine; EC 1.13.11.54; Oxidoreductase Chromosomal Location of Human Ortholog: 2p25.3 Cellular Component: nucleoplasm; Golgi apparatus; cytoplasm; plasma membrane; nucleus; cytosol Molecular Function:acireductone dioxygenase [iron(II)-requiring] activity; protein binding; iron ion binding; oxidoreductase activity Biological Process: methionine salvage; sulfur amino acid metabolic process; polyamine metabolic process |
| UniProt Code: | Q9BV57 |
| NCBI GenInfo Identifier: | 74733289 |
| NCBI Gene ID: | 55256 |
| NCBI Accession: | Q9BV57.1 |
| Molecular Weight: | 21kDa |
| NCBI Full Name: | 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase |
| UniProt Protein Name: | 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase |
| UniProt Synonym Protein Names: | Acireductone dioxygenase (Fe(2+)-requiring); Membrane-type 1 matrix metalloproteinase cytoplasmic tail-binding protein 1 |
| Protein Family: | 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase |
| UniProt Gene Name: | ADI1 |
| UniProt Entry Name: | MTND_HUMAN |
