Description
| 抗体名: | ACOX2 Antibody (PACO07565) |
| 抗体コード: | PACO07565 |
| サイズ: | 50ul |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, IHC, IF |
| 推奨される希釈: | |
| 反応性: | Human, Mouse, Rat |
| 免疫原: | Human ACOX2 |
| 憲法: | Liquid |
| ストレージバッファ: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| 精製方法: | Antigen Affinity purified |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
| シノニム: | acyl-Coenzyme A oxidase 2, branched chain;ACOX2;BCOX;BRCACOX;BRCOX;THCCox ; |
| UniProt Protein Function: | ACOX2: Oxidizes the CoA esters of the bile acid intermediates di- and tri-hydroxycholestanoic acids. Belongs to the acyl-CoA oxidase family. |
| UniProt Protein Details: | Protein type:EC 1.17.99.3; Lipid Metabolism - primary bile acid biosynthesis; Oxidoreductase Chromosomal Location of Human Ortholog: 3p14.3 Cellular Component: intracellular membrane-bound organelle; mitochondrion; peroxisomal matrix; peroxisome Molecular Function:acyl-CoA binding; acyl-CoA dehydrogenase activity; acyl-CoA oxidase activity; electron carrier activity; FAD binding; pristanoyl-CoA oxidase activity; receptor binding Biological Process: bile acid biosynthetic process; fatty acid beta-oxidation using acyl-CoA dehydrogenase; fatty acid beta-oxidation using acyl-CoA oxidase; lipid homeostasis |
| NCBI Summary: | The product of this gene belongs to the acyl-CoA oxidase family. It encodes the branched-chain acyl-CoA oxidase which is involved in the degradation of long branched fatty acids and bile acid intermediates in peroxisomes. Deficiency of this enzyme results in the accumulation of branched fatty acids and bile acid intermediates, and may lead to Zellweger syndrome, severe mental retardation, and death in children. [provided by RefSeq, Mar 2009] |
| UniProt Code: | Q99424 |
| NCBI GenInfo Identifier: | 17366636 |
| NCBI Gene ID: | 8309 |
| NCBI Accession: | Q99424.1 |
| UniProt Secondary Accession: | Q99424,A6NF16, B2R8U5, |
| UniProt Related Accession: | Q99424 |
| Molecular Weight: | 76,827 Da |
| NCBI Full Name: | Peroxisomal acyl-coenzyme A oxidase 2 |
| NCBI Synonym Full Names: | acyl-CoA oxidase 2 |
| NCBI Official Symbol: | ACOX2 |
| NCBI Official Synonym Symbols: | BCOX; BRCOX; THCCox; BRCACOX |
| NCBI Protein Information: | peroxisomal acyl-coenzyme A oxidase 2 |
| UniProt Protein Name: | Peroxisomal acyl-coenzyme A oxidase 2 |
| UniProt Synonym Protein Names: | 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanoyl-CoA 24-hydroxylase; 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanoyl-CoA oxidase; Trihydroxycoprostanoyl-CoA oxidase; THCA-CoA oxidase; THCCox |
| Protein Family: | Peroxisomal acyl-coenzyme A oxidase |
| UniProt Gene Name: | ACOX2 |
| UniProt Entry Name: | ACOX2_HUMAN |
