Description
| 抗体名: | ABI2 Antibody (PACO07534) |
| 抗体コード: | PACO07534 |
| サイズ: | 50ul |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, WB, IF |
| 推奨される希釈: | |
| 反応性: | Human, Mouse, Rat |
| 免疫原: | Human ABI2 |
| 憲法: | Liquid |
| ストレージバッファ: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| 精製方法: | Antigen Affinity purified |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
| シノニム: | abl interactor 2;ABI2;ABI-2;ABI2B;AIP-1;AblBP3;SSH3BP2;argBPIA;argBPIB ; |
| UniProt Protein Function: | Abi-2: May act in regulation of cell growth and transformation by interacting with nonreceptor tyrosine kinases ABL1 and/or ABL2. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex. Regulates ABL1/c-Abl-mediated phosphorylation of MENA. Belongs to the ABI family. 4 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Adaptor/scaffold; Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 2q33 Cellular Component: cytoskeleton; lamellipodium; cytoplasm; cytosol; filopodium Molecular Function:protein binding; DNA binding; ubiquitin protein ligase binding; Rac GTPase binding; protein complex binding; cytoskeletal adaptor activity; kinase binding; SH3 domain binding Biological Process: cell migration; peptidyl-tyrosine phosphorylation; actin polymerization and/or depolymerization; Rac protein signal transduction; cytoskeleton organization and biogenesis; cell motility |
| UniProt Code: | Q9NYB9 |
| NCBI GenInfo Identifier: | 50400673 |
| NCBI Gene ID: | 10152 |
| NCBI Accession: | Q9NYB9.1 |
| UniProt Related Accession: | Q9NYB9 |
| Molecular Weight: | 56 kDa |
| NCBI Full Name: | Abl interactor 2 |
| NCBI Synonym Full Names: | abl interactor 2 |
| NCBI Official Symbol: | ABI2 |
| NCBI Official Synonym Symbols: | AIP1; ABI-2; ABI2B; AIP-1; AblBP3; argBP1; SSH3BP2; argBPIA; argBPIB |
| NCBI Protein Information: | abl interactor 2 |
| UniProt Protein Name: | Abl interactor 2 |
| UniProt Synonym Protein Names: | Abelson interactor 2; Abi-2; Abl-binding protein 3; AblBP3; Arg-binding protein 1; ArgBP1 |
| Protein Family: | Abl interactor |
| UniProt Gene Name: | ABI2 |
| UniProt Entry Name: | ABI2_HUMAN |
