GCK Antibody (PACO43605)
- SKU:
- PACO43605
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | GCK Antibody (PACO43605) |
抗体コード: | PACO43605 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC |
推奨される希釈: | ELISA:1:2000-1:10000, WB:1:200-1:1000, IHC:1:20-1:200 |
反応性: | Human |
免疫原: | Recombinant Human Glucokinase protein (1-300AA) |
憲法: | Liquid |
ストレージバッファ: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
精製方法: | Antigen Affinity Purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
Western blot. All lanes: Glucokinase antibody at 8µg/ml + HepG2 whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 52 kDa. Observed band size: 52 kDa. | |
Immunohistochemistry of paraffin-embedded human pancreatic tissue using PACO43605 at dilution of 1:100. | |
Immunohistochemistry of paraffin-embedded human small intestine tissue using PACO43605 at dilution of 1:100. |
バックグラウンド: | Catalyzes the initial step in utilization of glucose by the beta-cell and liver at physiological glucose concentration. Glucokinase has a high Km for glucose, and so it is effective only when glucose is abundant. The role of GCK is to provide G6P for the synthesis of glycogen. Pancreatic glucokinase plays an important role in modulating insulin secretion. Hepatic glucokinase helps to facilitate the uptake and conversion of glucose by acting as an insulin-sensitive determinant of hepatic glucose usage. |
シノニム: | Glucokinase (EC 2.7.1.2) (Hexokinase type IV) (HK IV) (Hexokinase-4) (HK4) (Hexokinase-D), GCK |
UniProt Code: | P35557 |
NCBI GenInfo Identifier: | 547696 |
NCBI Gene ID: | 2645 |
NCBI Accession: | P35557.1 |
UniProt Secondary Accession: | P35557,Q05810, A4D2J2, A4D2J3, |
UniProt Related Accession: | P35557 |
Molecular Weight: | 465 |
NCBI Full Name: | Glucokinase |
NCBI Synonym Full Names: | glucokinase (hexokinase 4) |
NCBI Official Symbol: | GCK |
NCBI Official Synonym Symbols: | GK; GLK; HK4; HHF3; HKIV; HXKP; LGLK; MODY2; FGQTL3 |
NCBI Protein Information: | glucokinase; HK IV; hexokinase-4; hexokinase-D; hexokinase type IV; hexokinase D, pancreatic isozyme; ATP:D-hexose 6-phosphotransferase |
UniProt Protein Name: | Glucokinase |
UniProt Synonym Protein Names: | Hexokinase type IV; HK IV; Hexokinase-4; HK4; Hexokinase-D |
UniProt Gene Name: | GCK |
UniProt Entry Name: | HXK4_HUMAN |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |