GCK Antibody (PACO16401)
- SKU:
- PACO16401
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | GCK Antibody (PACO16401) |
抗体コード: | PACO16401 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC |
推奨される希釈: | ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:50-1:200 |
反応性: | Human, Mouse, Rat |
免疫原: | Fusion protein of human GCK |
憲法: | Liquid |
ストレージバッファ: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
精製方法: | Antigen affinity purification |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO16401(GCK Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: x200). | |
Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: HT29 cells, Primary antibody: PACO16401(GCK Antibody) at dilution 1/450, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 40 seconds. | |
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO16401(GCK Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: x200). |
バックグラウンド: | Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. Alternative splicing of this gene results in three tissue-specific forms of glucokinase, one found in pancreatic islet β cells and two found in liver. The protein localizes to the outer membrane of mitochondria. In contrast to other forms of hexokinase, this enzyme is not inhibited by its product glucose-6-phosphate but remains active while glucose is abundant. Mutations in this gene have been associated with non-insulin dependent diabetes mellitus (NIDDM), maturity onset diabetes of the young, type 2 (MODY2) and persistent hyperinsulinemic hypoglycemia of infancy (PHHI). |
シノニム: | glucokinase (hexokinase 4) |
UniProt Code: | P35557 |
NCBI GenInfo Identifier: | 547696 |
NCBI Gene ID: | 2645 |
NCBI Accession: | P35557.1 |
UniProt Secondary Accession: | P35557,Q05810, A4D2J2, A4D2J3, |
UniProt Related Accession: | P35557 |
Molecular Weight: | 465 |
NCBI Full Name: | Glucokinase |
NCBI Synonym Full Names: | glucokinase (hexokinase 4) |
NCBI Official Symbol: | GCK |
NCBI Official Synonym Symbols: | GK; GLK; HK4; HHF3; HKIV; HXKP; LGLK; MODY2; FGQTL3 |
NCBI Protein Information: | glucokinase; HK IV; hexokinase-4; hexokinase-D; hexokinase type IV; hexokinase D, pancreatic isozyme; ATP:D-hexose 6-phosphotransferase |
UniProt Protein Name: | Glucokinase |
UniProt Synonym Protein Names: | Hexokinase type IV; HK IV; Hexokinase-4; HK4; Hexokinase-D |
UniProt Gene Name: | GCK |
UniProt Entry Name: | HXK4_HUMAN |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |