Anti-GUCY1B3 Antibody (CAB15276)
- SKU:
- CAB15276
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
抗体名: | Anti-GUCY1B3 Antibody |
抗体コード: | CAB15276 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IHC |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human GUCY1B3 (NP_000848.1). |
申し込み: | WB IHC |
推奨希釈: | WB 1:200 - 1:2000 IHC 1:50 - 1:200 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | Mouse brain, Rat lung, Rat brain |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human GUCY1B3 (NP_000848.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | MYGF VNHA LELL VIRN YGPE VWED IKKE AQLD EEGQ FLVR IIYD DSKT YDLV AAAS KVLN LNAG EILQ MFGK MFFV FCQE SGYD TILR VLGS NVRE FLQN LDAL HDHL ATIY PGMR APSF RCTD AEKG KGLI LHYY SERE GLQD IVIG IIKT VAQQ IHGT EIDM KVIQ QRNE ECDH TQFL IEEK ESKE EDFY EDLD RFEE NGTQ ESRI SPYT FCKA FPFH IIFD RDLV VTQC GNAI YRVL PQLQ PGNC SL |
遺伝子ID: | 2983 |
Uniprot: | Q02153 |
セルラーロケーション: | Cytoplasm |
計算された分子量: | 66kDa/68kDa/70kDa |
観察された分子量: | 70kDa |
同義語: | GUCY1B3, GC-S-beta-1, GC-SB3, GUC1B3, GUCB3, GUCSB3, GUCY1B1 |
バックグラウンド: | This gene encodes the beta subunit of the soluble guanylate cyclase (sGC), which catalyzes the conversion of GTP (guanosine triphosphate) to cGMP (cyclic guanosine monophosphate). The encoded protein contains an HNOX domain, which serves as a receptor for ligands such as nitric oxide, oxygen and nitrovasodilator drugs. Alternative splicing results in multiple transcript variants. |
UniProt Protein Function: | GUCY1B3: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. Heterodimer of an alpha and a beta chain. 2 isoforms of the human protein are produced by alternative splicing |
UniProt Protein Details: | Protein type:Receptor, misc.; Guanylyl cyclase; Lyase; Nucleotide Metabolism - purine; EC 4.6.1.2 Chromosomal Location of Human Ortholog: 4q31.3-q33 Cellular Component: guanylate cyclase complex, soluble; intracellular membrane-bound organelle; cytoplasm Molecular Function:guanylate cyclase activity; GTP binding; protein heterodimerization activity; metal ion binding; heme binding; Hsp90 protein binding; receptor activity Biological Process: cGMP biosynthetic process; blood circulation; blood coagulation; nitric oxide mediated signal transduction |
NCBI Summary: | This gene encodes the beta subunit of the soluble guanylate cyclase (sGC), which catalyzes the conversion of GTP (guanosine triphosphate) to cGMP (cyclic guanosine monophosphate). The encoded protein contains an HNOX domain, which serves as a receptor for ligands such as nitric oxide, oxygen and nitrovasodilator drugs. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014] |
UniProt Code: | Q02153 |
NCBI GenInfo Identifier: | 399328 |
NCBI Gene ID: | 2983 |
NCBI Accession: | Q02153.1 |
UniProt Secondary Accession: | Q02153,Q86WY5, B7Z426, |
UniProt Related Accession: | Q02153 |
Molecular Weight: | 619 |
NCBI Full Name: | Guanylate cyclase soluble subunit beta-1 |
NCBI Synonym Full Names: | guanylate cyclase 1, soluble, beta 3 |
NCBI Official Symbol: | GUCY1B3 |
NCBI Official Synonym Symbols: | GUCB3; GC-SB3; GUC1B3; GUCSB3; GUCY1B1; GC-S-beta-1 |
NCBI Protein Information: | guanylate cyclase soluble subunit beta-1; GCS-beta-1; GCS-beta-3; soluble guanylate cyclase small subunit; guanylate cyclase soluble subunit beta-3 |
UniProt Protein Name: | Guanylate cyclase soluble subunit beta-1 |
UniProt Synonym Protein Names: | Guanylate cyclase soluble subunit beta-3; GCS-beta-3; Soluble guanylate cyclase small subunit |
Protein Family: | Guanylate cyclase soluble |
UniProt Gene Name: | GUCY1B3 |
UniProt Entry Name: | GCYB1_HUMAN |
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