Anti-Anti-TrkB Antibody (CAB19832)
- SKU:
- CAB19832
- Product type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- GP145-TrkB/GP95-TrkB
- Synonyms:
- Tkrb
- Synonyms:
- trk-B
- Synonyms:
- trkB
Description
抗体名: | Anti-TrkB Rabbit mAb |
抗体コード: | CAB19832 |
サイズ: | 20uL, 50uL, 100uL |
同義語: | GP145-TrkB/GP95-TrkB, Tkrb, trk-B, trkB |
申し込み: | WB |
反応性: | Mouse, Rat |
宿主種: | Rabbit |
免疫原: | A synthesized peptide derived from human Anti-TrkB |
申し込み: | WB |
推奨される希釈: | WB 1:500 - 1:2000 |
反応性: | Mouse, Rat |
ポジティブサンプル: | Mouse spinal cord, Mouse brain, Rat brain |
免疫原: | A synthesized peptide derived from human Anti-TrkB |
精製方法: | Affinity purification |
保管所: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | Email for sequence |
遺伝子ID: | 18212 |
Uniprot: | P15209 |
計算された分子量: | 90, 140kDa |
観察された分子量: | 90KDa/140KDa |
UniProt Protein Function: | TrkB: a receptor tyrosine kinase of the Trk family. Receptor for brain-derived neurotrophic factor (BDNF), neurotrophin-3, -4 and -5 but not nerve growth factor (NGF). Involved in the development and maintenance of the nervous system. Three splice variant isoforms have been described. |
UniProt Protein Details: | Protein type:Protein kinase, tyrosine (receptor); EC 2.7.10.1; Membrane protein, integral; Kinase, protein; Protein kinase, TK; TK group; Trk family Cellular Component: cell surface; rough endoplasmic reticulum; integral to plasma membrane; cell; postsynaptic density; dendrite; integral to membrane; dendritic spine; excitatory synapse; terminal button; perikaryon; cytosol; postsynaptic membrane; growth cone; membrane; cell soma; axon; cytoplasm; presynaptic active zone; plasma membrane; intracellular; nerve terminal; receptor complex; endosome Molecular Function:neurotrophin binding; protein homodimerization activity; ephrin receptor binding; nucleotide binding; transmembrane receptor protein tyrosine kinase activity; neurotrophin receptor activity; protein kinase activity; transferase activity; brain-derived neurotrophic factor receptor activity; protein binding; brain-derived neurotrophic factor binding; protein-tyrosine kinase activity; transferase activity, transferring phosphorus-containing groups; kinase activity; ATP binding Biological Process: mechanoreceptor differentiation; retinal rod cell development; peptidyl-tyrosine phosphorylation; protein amino acid autophosphorylation; multicellular organismal development; regulation of neurotransmitter secretion; regulation of dendrite development; neuron migration; protein amino acid phosphorylation; positive regulation of synaptic transmission, glutamatergic; neuron differentiation; positive regulation of MAPKKK cascade; positive regulation of cell proliferation; oligodendrocyte differentiation; feeding behavior; negative regulation of neuron apoptosis; regulation of metabolic process; vasculogenesis; cell differentiation; neuromuscular junction development; central nervous system neuron development; nervous system development; regulation of GTPase activity; brain-derived neurotrophic factor receptor signaling pathway; regulation of protein kinase B signaling cascade; learning; positive regulation of peptidyl-serine phosphorylation; positive regulation of phosphoinositide 3-kinase cascade; peripheral nervous system neuron development; glutamate secretion; long-term memory; regulation of MAPKKK cascade; positive regulation of axonogenesis; cerebral cortex development; phosphorylation; transmembrane receptor protein tyrosine kinase signaling pathway |
UniProt Code: | P15209 |
NCBI GenInfo Identifier: | 136237 |
NCBI Gene ID: | 18212 |
NCBI Accession: | P15209.1 |
UniProt Secondary Accession: | P15209,Q3TUF9, Q80WU0, Q91XJ9, |
UniProt Related Accession: | P15209 |
Molecular Weight: | 83,744 Da |
NCBI Full Name: | BDNF/NT-3 growth factors receptor |
NCBI Synonym Full Names: | neurotrophic tyrosine kinase, receptor, type 2 |
NCBI Official Symbol: | Ntrk2 |
NCBI Official Synonym Symbols: | Tkrb; trkB; trk-B; GP145-TrkB/GP95-TrkB |
NCBI Protein Information: | BDNF/NT-3 growth factors receptor; trkB tyrosine kinase; neurotrophic tyrosine receptor kinase type 2 |
UniProt Protein Name: | BDNF/NT-3 growth factors receptor |
UniProt Synonym Protein Names: | GP145-TrkB/GP95-TrkB; Trk-B; Neurotrophic tyrosine kinase receptor type 2; TrkB tyrosine kinase |
Protein Family: | BDNF/NT-3 growth factors receptor |
UniProt Gene Name: | Ntrk2 |
UniProt Entry Name: | NTRK2_MOUSE |