Anti-GABRB1 Antibody (CAB16015)
- SKU:
- CAB16015
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
抗体名: | Anti-GABRB1 Antibody |
抗体コード: | CAB16015 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | A synthetic peptide of human GABRB1 |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | U-251MG, mouse brain, rat brain |
免疫原: | A synthetic peptide of human GABRB1 |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | Email for sequence |
遺伝子ID: | 2560 |
Uniprot: | P18505 |
セルラーロケーション: | |
計算された分子量: | 10kDa/54kDa |
観察された分子量: | 54kDa |
同義語: | GABRB1, EIEE45 |
バックグラウンド: | The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes GABA A receptor, beta 1 subunit. It is mapped to chromosome 4p12 in a cluster comprised of genes encoding alpha 4, alpha 2 and gamma 1 subunits of the GABA A receptor. Alteration of this gene is implicated in the pathogenetics of schizophrenia. |
UniProt Protein Function: | GABRB1: GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRB1 sub-subfamily. |
UniProt Protein Details: | Protein type:Channel, chloride; Membrane protein, multi-pass; Membrane protein, integral; Transporter; Transporter, ion channel; Channel, ligand-gated Chromosomal Location of Human Ortholog: 4p12 Cellular Component: postsynaptic membrane; integral to plasma membrane; plasma membrane; cell junction Molecular Function:chloride channel activity; GABA-A receptor activity; ligand-gated ion channel activity; extracellular ligand-gated ion channel activity Biological Process: synaptic transmission; transport; ion transport; signal transduction; transmembrane transport |
NCBI Summary: | The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes GABA A receptor, beta 1 subunit. It is mapped to chromosome 4p12 in a cluster comprised of genes encoding alpha 4, alpha 2 and gamma 1 subunits of the GABA A receptor. Alteration of this gene is implicated in the pathogenetics of schizophrenia. [provided by RefSeq, Jul 2008] |
UniProt Code: | P18505 |
NCBI GenInfo Identifier: | 194097327 |
NCBI Gene ID: | 2560 |
NCBI Accession: | NP_000803.2 |
UniProt Related Accession: | P18505 |
Molecular Weight: | ~ 54kDa |
NCBI Full Name: | gamma-aminobutyric acid receptor subunit beta-1 |
NCBI Synonym Full Names: | gamma-aminobutyric acid type A receptor subunit beta1 |
NCBI Official Symbol: | GABRB1 |
NCBI Official Synonym Symbols: | EIEE45 |
NCBI Protein Information: | gamma-aminobutyric acid receptor subunit beta-1 |
UniProt Protein Name: | Gamma-aminobutyric acid receptor subunit beta-1 |
UniProt Synonym Protein Names: | GABA(A) receptor subunit beta-1 |
UniProt Gene Name: | GABRB1 |
UniProt Entry Name: | GBRB1_HUMAN |
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