GABRB1 Antibody (PACO09387)
- SKU:
- PACO09387
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
| 抗体名: | GABRB1 Antibody (PACO09387) |
| 抗体コード: | PACO09387 |
| サイズ: | 50ul |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, WB |
| 推奨される希釈: | |
| 反応性: | Human, Mouse, Rat |
| 免疫原: | Human GABRB1 |
| 憲法: | Liquid |
| ストレージバッファ: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| 精製方法: | Antigen Affinity purified |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
| シノニム: | gamma-aminobutyric acid, (GABA) A receptor, β 1; |
| UniProt Protein Function: | GABRB1: GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRB1 sub-subfamily. |
| UniProt Protein Details: | Protein type:Channel, chloride; Membrane protein, multi-pass; Membrane protein, integral; Transporter; Transporter, ion channel; Channel, ligand-gated Chromosomal Location of Human Ortholog: 4p12 Cellular Component: postsynaptic membrane; integral to plasma membrane; plasma membrane; cell junction Molecular Function:chloride channel activity; GABA-A receptor activity; ligand-gated ion channel activity; extracellular ligand-gated ion channel activity Biological Process: synaptic transmission; transport; ion transport; signal transduction; transmembrane transport |
| NCBI Summary: | The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes GABA A receptor, beta 1 subunit. It is mapped to chromosome 4p12 in a cluster comprised of genes encoding alpha 4, alpha 2 and gamma 1 subunits of the GABA A receptor. Alteration of this gene is implicated in the pathogenetics of schizophrenia. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P18505 |
| NCBI GenInfo Identifier: | 194097327 |
| NCBI Gene ID: | 2560 |
| NCBI Accession: | NP_000803.2 |
| UniProt Related Accession: | P18505 |
| Molecular Weight: | ~ 54kDa |
| NCBI Full Name: | gamma-aminobutyric acid receptor subunit beta-1 |
| NCBI Synonym Full Names: | gamma-aminobutyric acid type A receptor subunit beta1 |
| NCBI Official Symbol: | GABRB1 |
| NCBI Official Synonym Symbols: | EIEE45 |
| NCBI Protein Information: | gamma-aminobutyric acid receptor subunit beta-1 |
| UniProt Protein Name: | Gamma-aminobutyric acid receptor subunit beta-1 |
| UniProt Synonym Protein Names: | GABA(A) receptor subunit beta-1 |
| UniProt Gene Name: | GABRB1 |
| UniProt Entry Name: | GBRB1_HUMAN |