Anti-CERS5 Antibody (CAB17239)
- SKU:
- CAB17239
- Product type:
- Antibody
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
抗体名: | Anti-CERS5 Antibody |
抗体コード: | CAB17239 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Mouse, Rat |
宿主種: | Rabbit |
免疫原: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CERS5 (NP_001268660.1). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Mouse, Rat |
ポジティブサンプル: |
免疫原: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CERS5 (NP_001268660.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | MMKP RPKR FIAK PCAL CIGI EDSG PYQA QPNA ILEK VFIS ITKY PDKK RLEG LSKQ LDWN VRKI QCWF RHRR NQDK PPTL TKFC ESMW RFTF YLCI FCYG |
遺伝子ID: | 91012 |
Uniprot: | Q8N5B7 |
セルラーロケーション: | |
計算された分子量: | |
観察された分子量: | Refer to figures |
同義語: | CERS5, LASS5, Trh4 |
バックグラウンド: | This gene encodes a protein that belongs to the TLC (TRAM, LAG1 and CLN8 homology domains) family of proteins. The encoded protein functions in the synthesis of ceramide, a lipid molecule that is involved in a several cellular signaling pathways. Alternate splicing results in multiple transcript variants. |
UniProt Protein Function: | LASS5: May be either a bona fide (dihydro)ceramide synthase or a modulator of its activity. When overexpressed in cells is involved in the production of sphingolipids containing mainly one fatty acid donor (N-linked palmitoyl- (C16) ceramide) in a fumonisin B1-independent manner. |
UniProt Protein Details: | Protein type:Membrane protein, multi-pass; Membrane protein, integral; Transferase; EC 2.3.1.24; DNA-binding Chromosomal Location of Human Ortholog: 12q13.12 Cellular Component: endoplasmic reticulum; endoplasmic reticulum membrane; integral to membrane; nuclear membrane Molecular Function:DNA binding; sphingosine N-acyltransferase activity Biological Process: ceramide biosynthetic process; sphingolipid biosynthetic process |
NCBI Summary: | This gene encodes a protein that belongs to the TLC (TRAM, LAG1 and CLN8 homology domains) family of proteins. The encoded protein functions in the synthesis of ceramide, a lipid molecule that is involved in a several cellular signaling pathways. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013] |
UniProt Code: | Q8N5B7 |
NCBI GenInfo Identifier: | 22218345 |
NCBI Gene ID: | 91012 |
NCBI Accession: | NP_671723.1 |
UniProt Secondary Accession: | Q8N5B7,B4DV54, |
UniProt Related Accession: | Q8N5B7 |
Molecular Weight: | 39,259 Da |
NCBI Full Name: | ceramide synthase 5 isoform 1 |
NCBI Synonym Full Names: | ceramide synthase 5 |
NCBI Official Symbol: | CERS5 |
NCBI Official Synonym Symbols: | Trh4; LASS5 |
NCBI Protein Information: | ceramide synthase 5 |
UniProt Protein Name: | Ceramide synthase 5 |
UniProt Synonym Protein Names: | LAG1 longevity assurance homolog 5 |
UniProt Gene Name: | CERS5 |
UniProt Entry Name: | CERS5_HUMAN |
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