CERS5 Antibody, FITC conjugated (PACO54540)
- SKU:
- PACO54540
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- FITC
Frequently bought together:
Description
抗体名: | CERS5 Antibody, FITC conjugated (PACO54540) |
抗体コード: | PACO54540 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Ceramide synthase 5 protein (332-392AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | FITC |
バックグラウンド: | Dihydroceramide synthase. Catalyzes the acylation of sphingosine to form dihydroceramide, with high selectivity toward palmitoyl-CoA as acyl donor compared to stearoyl-CoA. Inhibited by fumonisin B1 (By similarity). |
シノニム: | Ceramide synthase 5 (CerS5) (EC 2.3.1.24) (LAG1 longevity assurance homolog 5), CERS5, LASS5 |
UniProt Protein Function: | LASS5: May be either a bona fide (dihydro)ceramide synthase or a modulator of its activity. When overexpressed in cells is involved in the production of sphingolipids containing mainly one fatty acid donor (N-linked palmitoyl- (C16) ceramide) in a fumonisin B1-independent manner. |
UniProt Protein Details: | Protein type:Membrane protein, multi-pass; Membrane protein, integral; Transferase; EC 2.3.1.24; DNA-binding Chromosomal Location of Human Ortholog: 12q13.12 Cellular Component: endoplasmic reticulum; endoplasmic reticulum membrane; integral to membrane; nuclear membrane Molecular Function:DNA binding; sphingosine N-acyltransferase activity Biological Process: ceramide biosynthetic process; sphingolipid biosynthetic process |
NCBI Summary: | This gene encodes a protein that belongs to the TLC (TRAM, LAG1 and CLN8 homology domains) family of proteins. The encoded protein functions in the synthesis of ceramide, a lipid molecule that is involved in a several cellular signaling pathways. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013] |
UniProt Code: | Q8N5B7 |
NCBI GenInfo Identifier: | 22218345 |
NCBI Gene ID: | 91012 |
NCBI Accession: | NP_671723.1 |
UniProt Secondary Accession: | Q8N5B7,B4DV54, |
UniProt Related Accession: | Q8N5B7 |
Molecular Weight: | 39,259 Da |
NCBI Full Name: | ceramide synthase 5 isoform 1 |
NCBI Synonym Full Names: | ceramide synthase 5 |
NCBI Official Symbol: | CERS5 |
NCBI Official Synonym Symbols: | Trh4; LASS5 |
NCBI Protein Information: | ceramide synthase 5 |
UniProt Protein Name: | Ceramide synthase 5 |
UniProt Synonym Protein Names: | LAG1 longevity assurance homolog 5 |
UniProt Gene Name: | CERS5 |
UniProt Entry Name: | CERS5_HUMAN |