CERS5 Antibody (PACO19929)
- SKU:
- PACO19929
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | CERS5 Antibody (PACO19929) |
抗体コード: | PACO19929 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC |
推奨される希釈: | ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:50-1:200 |
反応性: | Human, Mouse |
免疫原: | Synthetic peptide of human CERS5 |
憲法: | Liquid |
ストレージバッファ: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
精製方法: | Antigen affinity purification |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using PACO19929(CERS5 Antibody) at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: x200). | |
Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Human fetal brain tissue, Primary antibody: PACO19929(CERS5 Antibody) at dilution 1/350, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 minutes. | |
The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using PACO19929(CERS5 Antibody) at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: x200). |
バックグラウンド: | This gene encodes a protein that belongs to the TLC (TRAM, LAG1 and CLN8 homology domains) family of proteins. The encoded protein functions in the synthesis of ceramide, a lipid molecule that is involved in a several cellular signaling pathways. Alternate splicing results in multiple transcript variants. |
シノニム: | ceramide synthase 5 |
UniProt Protein Function: | LASS5: May be either a bona fide (dihydro)ceramide synthase or a modulator of its activity. When overexpressed in cells is involved in the production of sphingolipids containing mainly one fatty acid donor (N-linked palmitoyl- (C16) ceramide) in a fumonisin B1-independent manner. |
UniProt Protein Details: | Protein type:Membrane protein, multi-pass; Membrane protein, integral; Transferase; EC 2.3.1.24; DNA-binding Chromosomal Location of Human Ortholog: 12q13.12 Cellular Component: endoplasmic reticulum; endoplasmic reticulum membrane; integral to membrane; nuclear membrane Molecular Function:DNA binding; sphingosine N-acyltransferase activity Biological Process: ceramide biosynthetic process; sphingolipid biosynthetic process |
NCBI Summary: | This gene encodes a protein that belongs to the TLC (TRAM, LAG1 and CLN8 homology domains) family of proteins. The encoded protein functions in the synthesis of ceramide, a lipid molecule that is involved in a several cellular signaling pathways. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013] |
UniProt Code: | Q8N5B7 |
NCBI GenInfo Identifier: | 22218345 |
NCBI Gene ID: | 91012 |
NCBI Accession: | NP_671723.1 |
UniProt Secondary Accession: | Q8N5B7,B4DV54, |
UniProt Related Accession: | Q8N5B7 |
Molecular Weight: | 39,259 Da |
NCBI Full Name: | ceramide synthase 5 isoform 1 |
NCBI Synonym Full Names: | ceramide synthase 5 |
NCBI Official Symbol: | CERS5 |
NCBI Official Synonym Symbols: | Trh4; LASS5 |
NCBI Protein Information: | ceramide synthase 5 |
UniProt Protein Name: | Ceramide synthase 5 |
UniProt Synonym Protein Names: | LAG1 longevity assurance homolog 5 |
UniProt Gene Name: | CERS5 |
UniProt Entry Name: | CERS5_HUMAN |