POLA2 Antibody, FITC conjugated (PACO35380)

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SKU:
PACO35380
Product type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Application:
ELISA
Antibody type:
Polyclonal
Conjugation:
FITC
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Description

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抗体名:POLA2 Antibody, FITC conjugated (PACO35380)
抗体コード:PACO35380
サイズ:50ug
宿主種:Rabbit
申し込み:ELISA
推奨される希釈:
反応性:Human
免疫原:Recombinant Human DNA polymerase α subunit B protein (101-400AA)
憲法:Liquid
ストレージバッファ:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
精製方法:>95%, Protein G purified
抗体のクローン性:Polyclonal
アイソタイプ:IgG
Conjugate:FITC
バックグラウンド:May play an essential role at the early stage of chromosomal DNA replication by coupling the polymerase alpha/primase complex to the cellular replication machinery.
シノニム:DNA polymerase α subunit B (DNA polymerase α 70 kDa subunit), POLA2
UniProt Protein Function:POLA2: a DNA polymerase that may play an essential role at the early stage of chromosomal DNA replication by coupling the polymerase alpha/primase complex to the cellular replication machinery. DNA polymerase alpha-primase is a four subunit enzyme (subunits A, B, C and D), which is assembled throughout the cell cycle. The largest subunit (subunit A) has DNA polymerase activity, the two smallest subunits (subunits C and D) have DNA primase activity. Subunit B binds to subunit A. Phosphorylated in a cell cycle-dependent manner, in G2/M phase.
UniProt Protein Details:

Protein type:Nucleotide Metabolism - purine; Nucleotide Metabolism - pyrimidine; DNA replication

Chromosomal Location of Human Ortholog: 11q13.1

Cellular Component: nucleoplasm; alpha DNA polymerase:primase complex; cytoplasm

Molecular Function:DNA binding; protein heterodimerization activity; DNA-directed DNA polymerase activity

Biological Process: telomere maintenance via semi-conservative replication; DNA replication initiation; protein import into nucleus, translocation; telomere maintenance via recombination; mitotic cell cycle; DNA strand elongation during DNA replication; DNA replication; telomere maintenance; G1/S transition of mitotic cell cycle

UniProt Code:Q14181
NCBI GenInfo Identifier:90110415
NCBI Gene ID:23649
NCBI Accession:Q14181.2
UniProt Secondary Accession:Q14181,Q9BPV3, B4DNB4,
UniProt Related Accession:Q14181
Molecular Weight:598
NCBI Full Name:DNA polymerase alpha subunit B
NCBI Synonym Full Names:polymerase (DNA directed), alpha 2, accessory subunit
NCBI Official Symbol:POLA2  
NCBI Protein Information:DNA polymerase alpha subunit B; DNA polymerase alpha 70 kDa subunit; polymerase (DNA-directed), alpha (70kD); polymerase (DNA directed), alpha 2 (70kD subunit)
UniProt Protein Name:DNA polymerase alpha subunit B
UniProt Synonym Protein Names:DNA polymerase alpha 70 kDa subunit
Protein Family:DNA polymerase
UniProt Gene Name:POLA2  
UniProt Entry Name:DPOA2_HUMAN
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