Anti-POLA2 Antibody (CAB3400)
- SKU:
- CAB3400
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
抗体名: | Anti-POLA2 Antibody |
抗体コード: | CAB3400 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human POLA2 (NP_002680.2). |
申し込み: | WB |
推奨希釈: | WB 1:1000 - 1:3000 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | HeLa, A-549, Jurkat, HL-60, SW480, Mouse liver, Mouse lung |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human POLA2 (NP_002680.2). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | MSAS AQQL AEEL QIFG LDCE EALI EKLV ELCV QYGQ NEEG MVGE LIAF CTST HKVG LTSE ILNS FEHE FLSK RLSK ARHS TCKD SGHA GARD IVSI QELI EVEE EEEI LLNS YTTP SKGS QKRA ISTP ETPL TKRS VSTR SPHQ LLSP SSFS PSAT PSQK YNSR SNRG EVVT SFGL AQGV SWSG RGGA GNIS LKVL GCPE ALTG SYKS MFQK LPDI REVL TCKI EELG SELK EHYK IEAF TPLL APAQ EP |
遺伝子ID: | 23649 |
Uniprot: | Q14181 |
セルラーロケーション: | Nucleus |
計算された分子量: | 40kDa/65kDa |
観察された分子量: | 70kDa |
同義語: | POLA2 |
バックグラウンド: |
UniProt Protein Function: | POLA2: a DNA polymerase that may play an essential role at the early stage of chromosomal DNA replication by coupling the polymerase alpha/primase complex to the cellular replication machinery. DNA polymerase alpha-primase is a four subunit enzyme (subunits A, B, C and D), which is assembled throughout the cell cycle. The largest subunit (subunit A) has DNA polymerase activity, the two smallest subunits (subunits C and D) have DNA primase activity. Subunit B binds to subunit A. Phosphorylated in a cell cycle-dependent manner, in G2/M phase. |
UniProt Protein Details: | Protein type:Nucleotide Metabolism - purine; Nucleotide Metabolism - pyrimidine; DNA replication Chromosomal Location of Human Ortholog: 11q13.1 Cellular Component: nucleoplasm; alpha DNA polymerase:primase complex; cytoplasm Molecular Function:DNA binding; protein heterodimerization activity; DNA-directed DNA polymerase activity Biological Process: telomere maintenance via semi-conservative replication; DNA replication initiation; protein import into nucleus, translocation; telomere maintenance via recombination; mitotic cell cycle; DNA strand elongation during DNA replication; DNA replication; telomere maintenance; G1/S transition of mitotic cell cycle |
UniProt Code: | Q14181 |
NCBI GenInfo Identifier: | 90110415 |
NCBI Gene ID: | 23649 |
NCBI Accession: | Q14181.2 |
UniProt Secondary Accession: | Q14181,Q9BPV3, B4DNB4, |
UniProt Related Accession: | Q14181 |
Molecular Weight: | 598 |
NCBI Full Name: | DNA polymerase alpha subunit B |
NCBI Synonym Full Names: | polymerase (DNA directed), alpha 2, accessory subunit |
NCBI Official Symbol: | POLA2 |
NCBI Protein Information: | DNA polymerase alpha subunit B; DNA polymerase alpha 70 kDa subunit; polymerase (DNA-directed), alpha (70kD); polymerase (DNA directed), alpha 2 (70kD subunit) |
UniProt Protein Name: | DNA polymerase alpha subunit B |
UniProt Synonym Protein Names: | DNA polymerase alpha 70 kDa subunit |
Protein Family: | DNA polymerase |
UniProt Gene Name: | POLA2 |
UniProt Entry Name: | DPOA2_HUMAN |
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