PDE1C Antibody, FITC conjugated (PACO50600)
- SKU:
- PACO50600
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- FITC
Frequently bought together:
Description
抗体名: | PDE1C Antibody, FITC conjugated (PACO50600) |
抗体コード: | PACO50600 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C protein (542-634AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | FITC |
バックグラウンド: | Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Has a high affinity for both cAMP and cGMP. |
シノニム: | Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (Cam-PDE 1C) (EC 3.1.4.17) (hCam-3), PDE1C |
UniProt Protein Function: | PDE1C: Cyclic nucleotide phosphodiesterase with a dual- specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Has a high affinity for both cAMP and cGMP. Belongs to the cyclic nucleotide phosphodiesterase family. PDE1 subfamily. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Nucleotide Metabolism - purine; Phosphodiesterase; EC 3.1.4.17 Chromosomal Location of Human Ortholog: 7p14.3 Cellular Component: cytosol Molecular Function:calmodulin-dependent cyclic-nucleotide phosphodiesterase activity |
NCBI Summary: | This gene encodes an enzyme that belongs to the 3'5'-cyclic nucleotide phosphodiesterase family. Members of this family catalyze hydrolysis of the cyclic nucleotides, cyclic adenosine monophosphate and cyclic guanosine monophosphate, to the corresponding nucleoside 5'-monophosphates. The enzyme encoded by this gene regulates proliferation and migration of vascular smooth muscle cells, and neointimal hyperplasia. This enzyme also plays a role in pathological vascular remodeling by regulating the stability of growth factor receptors, such as PDGF-receptor-beta. [provided by RefSeq, Jul 2016] |
UniProt Code: | Q14123 |
NCBI GenInfo Identifier: | 2499445 |
NCBI Gene ID: | 5137 |
NCBI Accession: | Q14123.1 |
UniProt Secondary Accession: | Q14123,Q14124, Q8NB10, B3KPC6, E9PE92, |
UniProt Related Accession: | Q14123 |
Molecular Weight: | 86,896 Da |
NCBI Full Name: | Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C |
NCBI Synonym Full Names: | phosphodiesterase 1C |
NCBI Official Symbol: | PDE1C |
NCBI Official Synonym Symbols: | Hcam3; hCam-3; cam-PDE 1C |
NCBI Protein Information: | calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C |
UniProt Protein Name: | Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C |
UniProt Synonym Protein Names: | hCam-3 |
Protein Family: | Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase |
UniProt Gene Name: | PDE1C |
UniProt Entry Name: | PDE1C_HUMAN |