DLX1 Antibody, Biotin conjugated (PACO56787)
- SKU:
- PACO56787
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- Biotin
Frequently bought together:
Description
抗体名: | DLX1 Antibody, Biotin conjugated (PACO56787) |
抗体コード: | PACO56787 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Homeobox protein DLX-1 protein (8-114AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Biotin |
バックグラウンド: | Plays a role as a transcriptional activator or repressor. Inhibits several cytokine signaling pathways, such as TGFB1, activin-A/INHBA and BMP4 by interfering with the transcriptional stimulatory activity of transcription factors, such as MSX2, FAST2, SMAD2 and SMAD3 during hematopoietic cell differentiation. Plays a role in terminal differentiation of interneurons, such as amacrine and bipolar cells in the developing retina (By similarity). Likely to play a regulatory role in the development of the ventral forebrain (By similarity). May play a role in craniofacial patterning and morphogenesis and may be involved in the early development of diencephalic subdivisions (By similarity). |
シノニム: | Homeobox protein DLX-1, DLX1 |
UniProt Protein Function: | Plays a role as a transcriptional activator or repressor (PubMed:14671321). Inhibits several cytokine signaling pathways, such as TGFB1, activin-A/INHBA and BMP4 by interfering with the transcriptional stimulatory activity of transcription factors, such as MSX2, FAST2, SMAD2 and SMAD3 during hematopoietic cell differentiation (PubMed:14671321). Plays a role in terminal differentiation of interneurons, such as amacrine and bipolar cells in the developing retina. Likely to play a regulatory role in the development of the ventral forebrain. May play a role in craniofacial patterning and morphogenesis and may be involved in the early development of diencephalic subdivisions. |
NCBI Summary: | This gene encodes a member of a homeobox transcription factor gene family similiar to the Drosophila distal-less gene. The encoded protein is localized to the nucleus where it may function as a transcriptional regulator of signals from multiple TGF-{beta} superfamily members. The encoded protein may play a role in the control of craniofacial patterning and the differentiation and survival of inhibitory neurons in the forebrain. This gene is located in a tail-to-tail configuration with another member of the family on the long arm of chromosome 2. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008] |
UniProt Code: | P56177 |
NCBI GenInfo Identifier: | 84043956 |
NCBI Gene ID: | 1745 |
NCBI Accession: | NP_001033582.1 |
UniProt Secondary Accession: | P56177,Q53ZU4, Q7Z724, Q8IYB2, D3DPD7, |
UniProt Related Accession: | P56177 |
Molecular Weight: | |
NCBI Full Name: | homeobox protein DLX-1 isoform 2 |
NCBI Synonym Full Names: | distal-less homeobox 1 |
NCBI Official Symbol: | DLX1 |
NCBI Protein Information: | homeobox protein DLX-1 |
UniProt Protein Name: | Homeobox protein DLX-1 |
Protein Family: | Homeobox protein |
UniProt Gene Name: | DLX1 |