Anti-DLX1 Antibody (CAB17381)

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SKU:
CAB17381
Product type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Developmental Biology
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Description

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抗体名:Anti-DLX1 Antibody
抗体コード:CAB17381
抗体サイズ:20uL, 50uL, 100uL
申し込み:WB
反応性:Human, Mouse, Rat
宿主種:Rabbit
免疫原:Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human DLX1 (NP_835221.2).
申し込み:WB
推奨希釈:WB 1:500 - 1:2000
反応性:Human, Mouse, Rat
ポジティブサンプル:
免疫原:Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human DLX1 (NP_835221.2).
精製方法:Affinity purification
ストレージバッファ:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
アイソタイプ:IgG
順序:MTMT TMPE SLNS PVSG KAVF MEFG PPNQ QMSP SPMS HGHY SMHC LHSA GHSQ PDGA YSSA SSFS RPLG YPYV NSVS SHAS SPYI SSVQ SYPG SASL AQSR LEDP GADS EKST VVEG GEVR
遺伝子ID:1745
Uniprot:P56177
セルラーロケーション:
計算された分子量:
観察された分子量:Refer to figures
同義語:DLX1
バックグラウンド:This gene encodes a member of a homeobox transcription factor gene family similiar to the Drosophila distal-less gene. The encoded protein is localized to the nucleus where it may function as a transcriptional regulator of signals from multiple TGF-{beta} superfamily members. The encoded protein may play a role in the control of craniofacial patterning and the differentiation and survival of inhibitory neurons in the forebrain. This gene is located in a tail-to-tail configuration with another member of the family on the long arm of chromosome 2. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
UniProt Protein Function:Plays a role as a transcriptional activator or repressor (PubMed:14671321). Inhibits several cytokine signaling pathways, such as TGFB1, activin-A/INHBA and BMP4 by interfering with the transcriptional stimulatory activity of transcription factors, such as MSX2, FAST2, SMAD2 and SMAD3 during hematopoietic cell differentiation (PubMed:14671321). Plays a role in terminal differentiation of interneurons, such as amacrine and bipolar cells in the developing retina. Likely to play a regulatory role in the development of the ventral forebrain. May play a role in craniofacial patterning and morphogenesis and may be involved in the early development of diencephalic subdivisions.
NCBI Summary:This gene encodes a member of a homeobox transcription factor gene family similiar to the Drosophila distal-less gene. The encoded protein is localized to the nucleus where it may function as a transcriptional regulator of signals from multiple TGF-{beta} superfamily members. The encoded protein may play a role in the control of craniofacial patterning and the differentiation and survival of inhibitory neurons in the forebrain. This gene is located in a tail-to-tail configuration with another member of the family on the long arm of chromosome 2. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
UniProt Code:P56177
NCBI GenInfo Identifier:84043956
NCBI Gene ID:1745
NCBI Accession:NP_001033582.1
UniProt Secondary Accession:P56177,Q53ZU4, Q7Z724, Q8IYB2, D3DPD7,
UniProt Related Accession:P56177
Molecular Weight:
NCBI Full Name:homeobox protein DLX-1 isoform 2
NCBI Synonym Full Names:distal-less homeobox 1
NCBI Official Symbol:DLX1  
NCBI Protein Information:homeobox protein DLX-1
UniProt Protein Name:Homeobox protein DLX-1
Protein Family:Homeobox protein
UniProt Gene Name:DLX1  
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