DDAH2 Antibody (PACO19549)
- SKU:
- PACO19549
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | DDAH2 Antibody (PACO19549) |
抗体コード: | PACO19549 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC |
推奨される希釈: | ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:25-1:100 |
反応性: | Human, Mouse, Rat |
免疫原: | Synthetic peptide of human DDAH2 |
憲法: | Liquid |
ストレージバッファ: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
精製方法: | Antigen affinity purification |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO19549(DDAH2 Antibody) at dilution 1/15, on the right is treated with synthetic peptide. (Original magnification: x200). | |
Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane: Human fetal brain tissue, Primary antibody: PACO19549(DDAH2 Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 30 seconds. | |
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO19549(DDAH2 Antibody) at dilution 1/15, on the right is treated with synthetic peptide. (Original magnification: x200). |
バックグラウンド: | This gene belongs to the dimethylarginine dimethylaminohydrolase (DDAH) gene family. The encoded enzyme plays a role in nitric oxide generation by regulating cellular concentrations of methylarginines, which in turn inhibit nitric oxide synthase activity. |
シノニム: | dimethylarginine dimethylaminohydrolase 2 |
UniProt Protein Function: | DDAH2: Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in the regulation of nitric oxide generation. Belongs to the DDAH family. |
UniProt Protein Details: | Protein type:EC 3.5.3.18; Apoptosis; Hydrolase Chromosomal Location of Human Ortholog: 6p21.3 Cellular Component: centrosome; mitochondrion; cytoplasm Molecular Function:amino acid binding; protein binding; dimethylargininase activity; catalytic activity Biological Process: positive regulation of nitric oxide biosynthetic process; citrulline metabolic process; arginine catabolic process; nitric oxide biosynthetic process; nitric oxide mediated signal transduction; negative regulation of apoptosis |
NCBI Summary: | This gene encodes a dimethylarginine dimethylaminohydrolase. The encoded enzyme functions in nitric oxide generation by regulating the cellular concentrations of methylarginines, which in turn inhibit nitric oxide synthase activity. The protein may be localized to the mitochondria. Alternative splicing resulting in multiple transcript variants. [provided by RefSeq, Dec 2014] |
UniProt Code: | O95865 |
NCBI GenInfo Identifier: | 6831529 |
NCBI Gene ID: | 23564 |
NCBI Accession: | O95865.1 |
UniProt Related Accession: | O95865 |
Molecular Weight: | ~ 30kDa |
NCBI Full Name: | N(G),N(G)-dimethylarginine dimethylaminohydrolase 2 |
NCBI Synonym Full Names: | dimethylarginine dimethylaminohydrolase 2 |
NCBI Official Symbol: | DDAH2 |
NCBI Official Synonym Symbols: | G6a; DDAH; NG30; DDAHII; HEL-S-277 |
NCBI Protein Information: | N(G),N(G)-dimethylarginine dimethylaminohydrolase 2 |
UniProt Protein Name: | N(G),N(G)-dimethylarginine dimethylaminohydrolase 2 |
UniProt Synonym Protein Names: | DDAHII; Dimethylargininase-2; Protein G6a; S-phase protein |
Protein Family: | N(G),N(G)-dimethylarginine dimethylaminohydrolase |
UniProt Gene Name: | DDAH2 |
UniProt Entry Name: | DDAH2_HUMAN |
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