DDAH2 Antibody, Biotin conjugated (PACO26180)
- SKU:
- PACO26180
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- Biotin
Frequently bought together:
Description
抗体名: | DDAH2 Antibody, Biotin conjugated (PACO26180) |
抗体コード: | PACO26180 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human N(G),N(G)-dimethylarginine dimethylaminohydrolase 2 protein (1-285AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Biotin |
バックグラウンド: | Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in the regulation of nitric oxide generation. |
シノニム: | N(G),N(G)-dimethylarginine dimethylaminohydrolase 2 (DDAH-2) (Dimethylarginine dimethylaminohydrolase 2) (EC 3.5.3.18) (DDAHII) (Dimethylargininase-2) (Protein G6a) (S-phase protein), DDAH2, DDAH G6A NG30 |
UniProt Protein Function: | DDAH2: Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in the regulation of nitric oxide generation. Belongs to the DDAH family. |
UniProt Protein Details: | Protein type:EC 3.5.3.18; Apoptosis; Hydrolase Chromosomal Location of Human Ortholog: 6p21.3 Cellular Component: centrosome; mitochondrion; cytoplasm Molecular Function:amino acid binding; protein binding; dimethylargininase activity; catalytic activity Biological Process: positive regulation of nitric oxide biosynthetic process; citrulline metabolic process; arginine catabolic process; nitric oxide biosynthetic process; nitric oxide mediated signal transduction; negative regulation of apoptosis |
NCBI Summary: | This gene encodes a dimethylarginine dimethylaminohydrolase. The encoded enzyme functions in nitric oxide generation by regulating the cellular concentrations of methylarginines, which in turn inhibit nitric oxide synthase activity. The protein may be localized to the mitochondria. Alternative splicing resulting in multiple transcript variants. [provided by RefSeq, Dec 2014] |
UniProt Code: | O95865 |
NCBI GenInfo Identifier: | 6831529 |
NCBI Gene ID: | 23564 |
NCBI Accession: | O95865.1 |
UniProt Related Accession: | O95865 |
Molecular Weight: | ~ 30kDa |
NCBI Full Name: | N(G),N(G)-dimethylarginine dimethylaminohydrolase 2 |
NCBI Synonym Full Names: | dimethylarginine dimethylaminohydrolase 2 |
NCBI Official Symbol: | DDAH2 |
NCBI Official Synonym Symbols: | G6a; DDAH; NG30; DDAHII; HEL-S-277 |
NCBI Protein Information: | N(G),N(G)-dimethylarginine dimethylaminohydrolase 2 |
UniProt Protein Name: | N(G),N(G)-dimethylarginine dimethylaminohydrolase 2 |
UniProt Synonym Protein Names: | DDAHII; Dimethylargininase-2; Protein G6a; S-phase protein |
Protein Family: | N(G),N(G)-dimethylarginine dimethylaminohydrolase |
UniProt Gene Name: | DDAH2 |
UniProt Entry Name: | DDAH2_HUMAN |