CENPA Antibody (PACO03355)
- SKU:
- PACO03355
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | CENPA Antibody |
抗体コード: | PACO03355 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, IHC |
推奨される希釈: | IHC:1:100-1:300 |
反応性: | Human |
免疫原: | synthesized peptide derived from the N-terminal region of human CENP-A. |
憲法: | Liquid |
ストレージバッファ: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
精製方法: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
シノニム: | CENPA; Histone H3-like centromeric protein A; Centromere autoantigen A; Centromere protein A; CENP-A |
UniProt Protein Function: | CENPA: a basic nuclear protein of the histone H3 family. May act as a core histone necessary for the assembly of centromeres. Contains a histone H3 related histone fold domain that is required for targeting to the centromere. CENPA is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces 1 or both copies of conventional histone H3 in the (H3-H4)2 tetrameric core of the nucleosome particle. |
UniProt Protein Details: | Protein type:DNA-binding Chromosomal Location of Human Ortholog: 2p23.3 Cellular Component: chromosome, pericentric region; condensed nuclear chromosome, pericentric region; cytosol; nucleoplasm; nucleus Molecular Function:chromatin binding; protein binding Biological Process: DNA replication-independent nucleosome assembly at centromere; establishment of mitotic spindle orientation; kinetochore assembly; sister chromatid cohesion |
NCBI Summary: | Centromeres are the differentiated chromosomal domains that specify the mitotic behavior of chromosomes. This gene encodes a centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere. Centromere protein A is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces 1 or both copies of conventional histone H3 in the (H3-H4)2 tetrameric core of the nucleosome particle. The protein is a replication-independent histone that is a member of the histone H3 family. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Nov 2015] |
UniProt Code: | P49450 |
NCBI GenInfo Identifier: | 1345726 |
NCBI Gene ID: | 1058 |
NCBI Accession: | P49450.1 |
UniProt Secondary Accession: | P49450,Q53T74, Q9BVW2, D6W544, |
UniProt Related Accession: | P49450 |
Molecular Weight: | 13,001 Da |
NCBI Full Name: | Histone H3-like centromeric protein A |
NCBI Synonym Full Names: | centromere protein A |
NCBI Official Symbol: | CENPA |
NCBI Official Synonym Symbols: | CenH3; CENP-A |
NCBI Protein Information: | histone H3-like centromeric protein A |
UniProt Protein Name: | Histone H3-like centromeric protein A |
UniProt Synonym Protein Names: | Centromere autoantigen A; Centromere protein A; CENP-A |
Protein Family: | Histone H3-like centromeric protein |
UniProt Gene Name: | CENPA |
UniProt Entry Name: | CENPA_HUMAN |