CEACAM5 Antibody (PACO21058)
- SKU:
- PACO21058
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | CEACAM5 Antibody (PACO21058) |
抗体コード: | PACO21058 |
サイズ: | 100ul(100ug) |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC |
推奨される希釈: | ELISA:1:2000-1:10000, WB:1:500-1:2000, IHC:1:50-1:200 |
反応性: | Human |
免疫原: | Recombinant protein of human CEACAM5 |
憲法: | Liquid |
ストレージバッファ: | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
精製方法: | Affinity purification |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
Western blot analysis of extracts of various cell lines, using CEACAM5 antibody. |
バックグラウンド: | Carcinoembryonic antigen (CEA), also known as CD66e or CEACAM5, is a 180-200 kDa cell surface glycoprotein whose expression is elevated in intestinal carcinomas and other tumors. CEA mediates cell adhesion, though little more is known about its biological activity. Expression of CEA is correlated with tumerogenicity, and it has been shown to play a role in cell migration, adhesion and invasion in culture cells, as well as in metastasis in vivo. |
シノニム: | CEACAM5;CD66e;CEA;DKFZp781M2392 |
UniProt Protein Function: | CEACAM5: Cell surface glycoprotein that plays a role in cell adhesion and in intracellular signaling. Receptor for E.coli Dr adhesins. Homodimer. Binding of E.coli Dr adhesins leads to dissociation of the homodimer. Found in adenocarcinomas of endodermally derived digestive system epithelium and fetal colon. Belongs to the immunoglobulin superfamily. CEA family. |
UniProt Protein Details: | Protein type:Membrane protein, integral; Immunoglobulin superfamily; Membrane protein, GPI anchor Chromosomal Location of Human Ortholog: 19q13.1-q13.2 Cellular Component: basolateral plasma membrane; integral to plasma membrane Molecular Function:identical protein binding; protein homodimerization activity Biological Process: homotypic cell-cell adhesion; negative regulation of apoptosis |
NCBI Summary: | Members of the CEACAM subfamily, including CEACAM5, belong to the CEA gene family. For general information on the CEA gene family, see CEACAM1 (MIM 109770).[supplied by OMIM, Oct 2009] |
UniProt Code: | P06731 |
NCBI GenInfo Identifier: | 317373456 |
NCBI Gene ID: | 1048 |
NCBI Accession: | P06731.3 |
UniProt Secondary Accession: | P06731,H9KVA7, |
UniProt Related Accession: | P06731 |
Molecular Weight: | 76,795 Da |
NCBI Full Name: | Carcinoembryonic antigen-related cell adhesion molecule 5 |
NCBI Synonym Full Names: | carcinoembryonic antigen-related cell adhesion molecule 5 |
NCBI Official Symbol: | CEACAM5 |
NCBI Official Synonym Symbols: | CEA; CD66e |
NCBI Protein Information: | carcinoembryonic antigen-related cell adhesion molecule 5; meconium antigen 100 |
UniProt Protein Name: | Carcinoembryonic antigen-related cell adhesion molecule 5 |
UniProt Synonym Protein Names: | Carcinoembryonic antigen; CEA; Meconium antigen 100 |
Protein Family: | Colicin |
UniProt Gene Name: | CEACAM5 |
UniProt Entry Name: | CEAM5_HUMAN |
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