C1GALT1 Antibody, Biotin conjugated (PACO58563)
- SKU:
- PACO58563
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- Biotin
Frequently bought together:
Description
抗体名: | C1GALT1 Antibody, Biotin conjugated (PACO58563) |
抗体コード: | PACO58563 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 protein (34-143AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Biotin |
バックグラウンド: | Glycosyltransferase that generates the core 1 O-glycan Gal-beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins. Plays a central role in many processes, such as angiogenesis, thrombopoiesis and kidney homeostasis development. |
シノニム: | Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 (EC 2.4.1.122) (B3Gal-T8) (Core 1 O-glycan T-synthase) (Core 1 UDP-galactose:N-acetylgalactosamine-alpha-R β 1,3-galactosyltransferase 1) (Beta-1,3-galactosyltransferase) (Core 1 beta1,3-galactosyltransferase 1) (C1GalT1) (Core 1 beta3-Gal-T1), C1GALT1 |
UniProt Protein Function: | C1GALT1: Glycosyltransferase that generates the core 1 O-glycan Gal-beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins. Plays a central role in many processes, such as angiogenesis, thrombopoiesis and kidney homeostasis development. Belongs to the glycosyltransferase 31 family. Beta3- Gal-T subfamily. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:EC 2.4.1.122; Glycan Metabolism - O-glycan biosynthesis; Transferase; Membrane protein, integral Chromosomal Location of Human Ortholog: 7p21.3 Cellular Component: Golgi membrane; integral to membrane Molecular Function:glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity; protein binding Biological Process: angiogenesis; kidney development; O-glycan processing; O-glycan processing, core 1 |
NCBI Summary: | The protein encoded by this gene generates the common core 1 O-glycan structure, Gal-beta-1-3GalNAc-R, by the transfer of Gal from UDP-Gal to GalNAc-alpha-1-R. Core 1 is a precursor for many extended mucin-type O-glycans on cell surface and secreted glycoproteins. Studies in mice suggest that this gene plays a key role in thrombopoiesis and kidney homeostasis.[provided by RefSeq, Sep 2010] |
UniProt Code: | Q9NS00 |
NCBI GenInfo Identifier: | 74719147 |
NCBI Gene ID: | 56913 |
NCBI Accession: | Q9NS00.1 |
UniProt Secondary Accession: | Q9NS00,Q96QH4, Q9BTU1, |
UniProt Related Accession: | Q9NS00 |
Molecular Weight: | 35,935 Da |
NCBI Full Name: | Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 |
NCBI Synonym Full Names: | core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 |
NCBI Official Symbol: | C1GALT1 |
NCBI Official Synonym Symbols: | C1GALT; T-synthase |
NCBI Protein Information: | glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 |
UniProt Protein Name: | Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 |
UniProt Synonym Protein Names: | B3Gal-T8; Core 1 O-glycan T-synthase; Core 1 UDP-galactose:N-acetylgalactosamine-alpha-R beta 1,3-galactosyltransferase 1; Beta-1,3-galactosyltransferase; Core 1 beta1,3-galactosyltransferase 1; C1GalT1; Core 1 beta3-Gal-T1 |
Protein Family: | C1GALT1-specific chaperone |
UniProt Gene Name: | C1GALT1 |
UniProt Entry Name: | C1GLT_HUMAN |