Anti-VAMP8 Antibody (CAB13915)
- SKU:
- CAB13915
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Autophagy
Frequently bought together:
Description
抗体名: | Anti-VAMP8 Antibody |
抗体コード: | CAB13915 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-75 of human VAMP8 (NP_003752.2). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | HeLa, NIH/3T3, PC-12, Mouse kidney, Mouse liver, Rat lung |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-75 of human VAMP8 (NP_003752.2). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | MEEA SEGG GNDR VRNL QSEV EGVK NIMT QNVE RILA RGEN LEHL RNKT EDLE ATSE HFKT TSQK VARK FWWK NVK |
遺伝子ID: | 8673 |
Uniprot: | Q9BV40 |
セルラーロケーション: | Cell membrane, Early endosome membrane, Late endosome membrane, Lysosome membrane, Single-pass type IV membrane protein |
計算された分子量: | 11kDa |
観察された分子量: | 11kDa |
同義語: | VAMP8, EDB, VAMP-8 |
バックグラウンド: | This gene encodes an integral membrane protein that belongs to the synaptobrevin/vesicle-associated membrane protein subfamily of soluble N-ethylmaleimide-sensitive factor attachment protein receptors (SNAREs). The encoded protein is involved in the fusion of synaptic vesicles with the presynaptic membrane. |
UniProt Protein Function: | VAMP8: Involved in the targeting and/or fusion of transport vesicles to their target membrane. Involved for dense-granule secretion in platelets. Plays a role in regulated enzyme secretion in pancreatic acinar cells. Involved in the abscission of the midbody during cell division, which leads to completely separate daughter cells. Involved in the homotypic fusion of early and late endosomes. Belongs to the synaptobrevin family. |
UniProt Protein Details: | Protein type:Membrane protein, integral; Vesicle Chromosomal Location of Human Ortholog: 2p12-p11.2 Cellular Component: cytoplasm; cytosol; early endosome; late endosome membrane; lysosomal membrane; membrane; perinuclear region of cytoplasm; plasma membrane; recycling endosome; secretory granule membrane; SNARE complex; vesicle Molecular Function:chloride channel inhibitor activity; protein binding; SNAP receptor activity; SNARE binding Biological Process: entry of virus into host cell; eosinophil degranulation; neutrophil degranulation; post-Golgi vesicle-mediated transport; vesicle fusion |
NCBI Summary: | This gene encodes an integral membrane protein that belongs to the synaptobrevin/vesicle-associated membrane protein subfamily of soluble N-ethylmaleimide-sensitive factor attachment protein receptors (SNAREs). The encoded protein is involved in the fusion of synaptic vesicles with the presynaptic membrane.[provided by RefSeq, Jun 2010] |
UniProt Code: | Q9BV40 |
NCBI GenInfo Identifier: | 55976764 |
NCBI Gene ID: | 8673 |
NCBI Accession: | Q9BV40.1 |
UniProt Secondary Accession: | Q9BV40,O60625, Q53SP9, Q6IB09, |
UniProt Related Accession: | Q9BV40 |
Molecular Weight: | 11,438 Da |
NCBI Full Name: | Vesicle-associated membrane protein 8 |
NCBI Synonym Full Names: | vesicle associated membrane protein 8 |
NCBI Official Symbol: | VAMP8 |
NCBI Official Synonym Symbols: | EDB; VAMP-8 |
NCBI Protein Information: | vesicle-associated membrane protein 8 |
UniProt Protein Name: | Vesicle-associated membrane protein 8 |
UniProt Synonym Protein Names: | Endobrevin |
Protein Family: | Vesicle-associated membrane protein |
UniProt Gene Name: | VAMP8 |
UniProt Entry Name: | VAMP8_HUMAN |
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