Anti-UBE3C Antibody (CAB6442)
- SKU:
- CAB6442
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
抗体名: | Anti-UBE3C Antibody |
抗体コード: | CAB6442 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IHC IF |
反応性: | Human |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human UBE3C (NP_055486.2). |
申し込み: | WB IHC IF |
推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:10 - 1:100 |
反応性: | Human |
ポジティブサンプル: | MCF7, BT-474, U-937, HT-29 |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human UBE3C (NP_055486.2). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | MFSF EGDF KTRP KVSL GGAS RKEE KASL LHRT QEER RKRE EERR RLKN AIII QSFI RGYR DRKQ QYSI QRSA FDRC ATLS QSGG AFPI ANGP NLTL LVRQ LLFF YKQN EDSK RLIW LYQN LIKH SSLF VKQL DGSE RLTC LFQI KRLM SLCC RLLQ NCND DSLN VALP MRML EVFS SENT YLPV LQDA SYVV SVIE QILH YMIH NGYY RSLY LLIN SKLP SSIE YSDL SRVP IAKI LLEN VLKP LHFT YNSC PEGA RQQV FTAF TEEF LA |
遺伝子ID: | 9690 |
Uniprot: | Q15386 |
セルラーロケーション: | Nucleus |
計算された分子量: | 45kDa/74kDa/123kDa |
観察された分子量: | 124kDa |
同義語: | UBE3C, HECTH2 |
バックグラウンド: |
UniProt Protein Function: | UBE3C: E3 ubiquitin-protein ligase that accepts ubiquitin from the E2 ubiquitin-conjugating enzyme UBE2D1 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Can assemble unanchored poly-ubiquitin chains in either 'Lys-29'- or 'Lys-48'-linked polyubiquitin chains. Has preference for 'Lys-48' linkages. It can target itself for ubiquitination in vitro and may promote its own degradation in vivo. 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:EC 6.3.2.19; Ligase; Ubiquitin conjugating system; EC 6.3.2.-; Ubiquitin ligase Chromosomal Location of Human Ortholog: 7q36.3 Cellular Component: proteasome complex; cytoplasm; intracellular; nucleus Molecular Function:protein binding; ubiquitin-protein ligase activity; ligase activity Biological Process: protein polyubiquitination; protein ubiquitination during ubiquitin-dependent protein catabolic process |
UniProt Code: | Q15386 |
NCBI GenInfo Identifier: | 67462009 |
NCBI Gene ID: | 9690 |
NCBI Accession: | Q15386.3 |
UniProt Secondary Accession: | Q15386,Q8TC15, Q96CR4, Q9UDU3, A4D235, A6NCP3, |
UniProt Related Accession: | Q15386 |
Molecular Weight: | |
NCBI Full Name: | Ubiquitin-protein ligase E3C |
NCBI Synonym Full Names: | ubiquitin protein ligase E3C |
NCBI Official Symbol: | UBE3C |
NCBI Official Synonym Symbols: | HECTH2 |
NCBI Protein Information: | ubiquitin-protein ligase E3C; ubiquitin-protein isopeptide ligase (E3) |
UniProt Protein Name: | Ubiquitin-protein ligase E3C |
UniProt Synonym Protein Names: | HectH2 |
Protein Family: | Ubiquitin-protein ligase |
UniProt Gene Name: | UBE3C |
UniProt Entry Name: | UBE3C_HUMAN |
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