UBE3C Antibody, HRP conjugated (PACO50579)
- SKU:
- PACO50579
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- HRP
Frequently bought together:
Description
抗体名: | UBE3C Antibody, HRP conjugated (PACO50579) |
抗体コード: | PACO50579 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Ubiquitin-protein ligase E3C protein (310-377AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | HRP |
バックグラウンド: | E3 ubiquitin-protein ligase that accepts ubiquitin from the E2 ubiquitin-conjugating enzyme UBE2D1 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Can assemble unanchored poly-ubiquitin chains in either 'Lys-29'- or 'Lys-48'-linked polyubiquitin chains. Has preference for 'Lys-48' linkages. It can target itself for ubiquitination in vitro and may promote its own degradation in vivo. |
シノニム: | Ubiquitin-protein ligase E3C (EC 2.3.2.26) (HECT-type ubiquitin transferase E3C) (HectH2), UBE3C, KIAA0010 KIAA10 |
UniProt Protein Function: | UBE3C: E3 ubiquitin-protein ligase that accepts ubiquitin from the E2 ubiquitin-conjugating enzyme UBE2D1 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Can assemble unanchored poly-ubiquitin chains in either 'Lys-29'- or 'Lys-48'-linked polyubiquitin chains. Has preference for 'Lys-48' linkages. It can target itself for ubiquitination in vitro and may promote its own degradation in vivo. 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:EC 6.3.2.19; Ligase; Ubiquitin conjugating system; EC 6.3.2.-; Ubiquitin ligase Chromosomal Location of Human Ortholog: 7q36.3 Cellular Component: proteasome complex; cytoplasm; intracellular; nucleus Molecular Function:protein binding; ubiquitin-protein ligase activity; ligase activity Biological Process: protein polyubiquitination; protein ubiquitination during ubiquitin-dependent protein catabolic process |
UniProt Code: | Q15386 |
NCBI GenInfo Identifier: | 67462009 |
NCBI Gene ID: | 9690 |
NCBI Accession: | Q15386.3 |
UniProt Secondary Accession: | Q15386,Q8TC15, Q96CR4, Q9UDU3, A4D235, A6NCP3, |
UniProt Related Accession: | Q15386 |
Molecular Weight: | |
NCBI Full Name: | Ubiquitin-protein ligase E3C |
NCBI Synonym Full Names: | ubiquitin protein ligase E3C |
NCBI Official Symbol: | UBE3C |
NCBI Official Synonym Symbols: | HECTH2 |
NCBI Protein Information: | ubiquitin-protein ligase E3C; ubiquitin-protein isopeptide ligase (E3) |
UniProt Protein Name: | Ubiquitin-protein ligase E3C |
UniProt Synonym Protein Names: | HectH2 |
Protein Family: | Ubiquitin-protein ligase |
UniProt Gene Name: | UBE3C |
UniProt Entry Name: | UBE3C_HUMAN |