Anti-TRIP13 Antibody (CAB17357)
- SKU:
- CAB17357
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Developmental Biology
Frequently bought together:
Description
抗体名: | Anti-TRIP13 Antibody |
抗体コード: | CAB17357 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human TRIP13 (NP_004228.1). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human |
ポジティブサンプル: | HeLa, PC-3 |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human TRIP13 (NP_004228.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, pH7.3. |
アイソタイプ: | IgG |
順序: | MDEA VGDL KQAL PCVA ESPT VHVE VHQR GSST AKKE DINL SVRK LLNR HNIV FGDY TWTE FDEP FLTR NVQS VSII DTEL KVKD SQPI DLSA CTVA LHIF QLNE DGPS SENL EEET ENII |
遺伝子ID: | 9319 |
Uniprot: | Q15645 |
セルラーロケーション: | |
計算された分子量: | 22kDa/48kDa |
観察された分子量: | 48kDa |
同義語: | TRIP13, 16E1BP |
バックグラウンド: | This gene encodes a protein that interacts with thyroid hormone receptors, also known as hormone-dependent transcription factors. The gene product interacts specifically with the ligand binding domain. This gene is one of several that may play a role in early-stage non-small cell lung cancer. |
UniProt Protein Function: | TRIP13: Plays a key role in chromosome recombination and chromosome structure development during meiosis. Required at early steps in meiotic recombination that leads to non-crossovers pathways. Also needed for efficient completion of homologous synapsis by influencing crossover distribution along the chromosomes affecting both crossovers and non-crossovers pathways. Also required for development of higher-order chromosome structures and is needed for synaptonemal-complex formation. In males, required for efficient synapsis of the sex chromosomes and for sex body formation. Promotes early steps of the DNA double- strand breaks (DSBs) repair process upstream of the assembly of RAD51 complexes. Required for depletion of HORMAD1 and HORMAD2 from synapsed chromosomes. Belongs to the AAA ATPase family. PCH2 subfamily. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Nuclear receptor co-regulator; Transcription, coactivator/corepressor Chromosomal Location of Human Ortholog: 5p15.33 Cellular Component: nucleus Molecular Function:identical protein binding; protein binding; transcription cofactor activity Biological Process: double-strand break repair; meiotic recombination; oogenesis; spermatogenesis; synaptonemal complex assembly; transcription from RNA polymerase II promoter |
NCBI Summary: | This gene encodes a protein that interacts with thyroid hormone receptors, also known as hormone-dependent transcription factors. The gene product interacts specifically with the ligand binding domain. This gene is one of several that may play a role in early-stage non-small cell lung cancer. [provided by RefSeq, Oct 2009] |
UniProt Code: | Q15645 |
NCBI GenInfo Identifier: | 85541056 |
NCBI Gene ID: | 9319 |
NCBI Accession: | Q15645.2 |
UniProt Secondary Accession: | Q15645,O15324, C9K0T3, D3DTC0, |
UniProt Related Accession: | Q15645 |
Molecular Weight: | 22,084 Da |
NCBI Full Name: | Pachytene checkpoint protein 2 homolog |
NCBI Synonym Full Names: | thyroid hormone receptor interactor 13 |
NCBI Official Symbol: | TRIP13 |
NCBI Official Synonym Symbols: | 16E1BP |
NCBI Protein Information: | pachytene checkpoint protein 2 homolog |
UniProt Protein Name: | Pachytene checkpoint protein 2 homolog |
UniProt Synonym Protein Names: | Human papillomavirus type 16 E1 protein-binding protein; 16E1-BP; HPV16 E1 protein-binding protein; Thyroid hormone receptor interactor 13; Thyroid receptor-interacting protein 13; TR-interacting protein 13; TRIP-13 |
UniProt Gene Name: | TRIP13 |
UniProt Entry Name: | PCH2_HUMAN |
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