Anti-SULT2B1 Antibody (CAB7736)
- SKU:
- CAB7736
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
抗体名: | Anti-SULT2B1 Antibody |
抗体コード: | CAB7736 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IHC IF |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-365 of human SULT2B1 (NP_814444.1). |
申し込み: | WB IHC IF |
推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:100 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | BT-474, HT-29, Mouse brain, Rat brain |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-365 of human SULT2B1 (NP_814444.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | MDGP AEPQ IPGL WDTY EDDI SEIS QKLP GEYF RYKG VPFP VGLY SLES ISLA ENTQ DVRD DDIF IITY PKSG TTWM IEII CLIL KEGD PSWI RSVP IWER APWC ETIV GAFS LPDQ YSPR LMSS HLPI QIFT KAFF SSKA KVIY MGRN PRDV VVSL YHYS KIAG QLKD PGTP DQFL RDFL KGEV QFGS WFDH IKGW LRMK GKDN FLFI TYEE LQQD LQGS VERI CGFL GRPL GKEA LGSV VAHS TFSA MKAN TMSN YTLL PPSL LDHR RGAF LRKG VCGD WKNH FTVA QSEA FDRA YRKQ MRGM PTFP WDED PEED GSPD PEPS PEPE PKPS LEPN TSLE REPR PNSS PSPS PGQA SETP HPRP S |
遺伝子ID: | 6820 |
Uniprot: | O00204 |
セルラーロケーション: | Cytoplasm, Microsome, Nucleus |
計算された分子量: | 39kDa/41kDa |
観察された分子量: | 41kDa |
同義語: | SULT2B1, HSST2 |
バックグラウンド: | Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene sulfates dehydroepiandrosterone but not 4-nitrophenol, a typical substrate for the phenol and estrogen sulfotransferase subfamilies. Two alternatively spliced variants that encode different isoforms have been described. |
UniProt Protein Function: | SULT2B1: Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs and xenobiotic compounds. Sulfonation increases the water solubility of most compounds, and therefore their renal excretion, but it can also result in bioactivation to form active metabolites. Sulfates hydroxysteroids like DHEA. Isoform 1 preferentially sulfonates cholesterol, and isoform 2 avidly sulfonates pregnenolone but not cholesterol. Belongs to the sulfotransferase 1 family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Transferase; Lipid Metabolism - androgen and estrogen; Energy Metabolism - sulfur; EC 2.8.2.2 Chromosomal Location of Human Ortholog: 19q13.3 Cellular Component: intracellular membrane-bound organelle; endoplasmic reticulum; cytoplasm; cytosol; nucleus Molecular Function:protein binding; alcohol sulfotransferase activity; steroid sulfotransferase activity Biological Process: steroid metabolic process; sulfate assimilation; xenobiotic metabolic process; 3'-phosphoadenosine 5'-phosphosulfate metabolic process |
NCBI Summary: | Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene sulfates dehydroepiandrosterone but not 4-nitrophenol, a typical substrate for the phenol and estrogen sulfotransferase subfamilies. Two alternatively spliced variants that encode different isoforms have been described. [provided by RefSeq] |
UniProt Code: | O00204 |
NCBI GenInfo Identifier: | 31563386 |
NCBI Gene ID: | 6820 |
NCBI Accession: | NP_814444.1 |
UniProt Secondary Accession: | O00204,O00205, O75814, |
UniProt Related Accession: | O00204 |
Molecular Weight: | 41,308 Da |
NCBI Full Name: | sulfotransferase family cytosolic 2B member 1 isoform b |
NCBI Synonym Full Names: | sulfotransferase family, cytosolic, 2B, member 1 |
NCBI Official Symbol: | SULT2B1 |
NCBI Official Synonym Symbols: | HSST2 |
NCBI Protein Information: | sulfotransferase family cytosolic 2B member 1; ST2B1; sulfotransferase 2B1; alcohol sulfotransferase; hydroxysteroid sulfotransferase 2 |
UniProt Protein Name: | Sulfotransferase family cytosolic 2B member 1 |
UniProt Synonym Protein Names: | Alcohol sulfotransferase; Hydroxysteroid sulfotransferase 2 |
Protein Family: | Sulfotransferase family cytosolic |
UniProt Gene Name: | SULT2B1 |
UniProt Entry Name: | ST2B1_HUMAN |
View AllClose