SULT2B1 Antibody (PACO43668)
- SKU:
- PACO43668
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Application:
- IP
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | SULT2B1 Antibody (PACO43668) |
抗体コード: | PACO43668 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC, IP |
推奨される希釈: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:20-1:200, IP:1:200-1:2000 |
反応性: | Human |
免疫原: | Recombinant Human Sulfotransferase family cytosolic 2B member 1 protein (1-365AA) |
憲法: | Liquid |
ストレージバッファ: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
精製方法: | Antigen Affinity Purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
Western blot. All lanes: Sulfotransferase family cytosolic 2B member 1 antibody at 4µg/ml + MCF-7 whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 42, 40 kDa. Observed band size: 42 kDa. | |
Immunohistochemistry of paraffin-embedded human placenta tissue using PACO43668 at dilution of 1:100. | |
Immunohistochemistry of paraffin-embedded human prostate tissue using PACO43668 at dilution of 1:100. |
バックグラウンド: | Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs and xenobiotic compounds. Sulfonation increases the water solubility of most compounds, and therefore their renal excretion, but it can also result in bioactivation to form active metabolites. Sulfates hydroxysteroids like DHEA. Isoform 1 preferentially sulfonates cholesterol, and isoform 2 avidly sulfonates pregnenolone but not cholesterol. |
シノニム: | Sulfotransferase family cytosolic 2B member 1 (ST2B1) (Sulfotransferase 2B1) (EC 2.8.2.2) (Alcohol sulfotransferase) (Hydroxysteroid sulfotransferase 2), SULT2B1, HSST2 |
UniProt Protein Function: | SULT2B1: Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs and xenobiotic compounds. Sulfonation increases the water solubility of most compounds, and therefore their renal excretion, but it can also result in bioactivation to form active metabolites. Sulfates hydroxysteroids like DHEA. Isoform 1 preferentially sulfonates cholesterol, and isoform 2 avidly sulfonates pregnenolone but not cholesterol. Belongs to the sulfotransferase 1 family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Transferase; Lipid Metabolism - androgen and estrogen; Energy Metabolism - sulfur; EC 2.8.2.2 Chromosomal Location of Human Ortholog: 19q13.3 Cellular Component: intracellular membrane-bound organelle; endoplasmic reticulum; cytoplasm; cytosol; nucleus Molecular Function:protein binding; alcohol sulfotransferase activity; steroid sulfotransferase activity Biological Process: steroid metabolic process; sulfate assimilation; xenobiotic metabolic process; 3'-phosphoadenosine 5'-phosphosulfate metabolic process |
NCBI Summary: | Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene sulfates dehydroepiandrosterone but not 4-nitrophenol, a typical substrate for the phenol and estrogen sulfotransferase subfamilies. Two alternatively spliced variants that encode different isoforms have been described. [provided by RefSeq] |
UniProt Code: | O00204 |
NCBI GenInfo Identifier: | 31563386 |
NCBI Gene ID: | 6820 |
NCBI Accession: | NP_814444.1 |
UniProt Secondary Accession: | O00204,O00205, O75814, |
UniProt Related Accession: | O00204 |
Molecular Weight: | 41,308 Da |
NCBI Full Name: | sulfotransferase family cytosolic 2B member 1 isoform b |
NCBI Synonym Full Names: | sulfotransferase family, cytosolic, 2B, member 1 |
NCBI Official Symbol: | SULT2B1 |
NCBI Official Synonym Symbols: | HSST2 |
NCBI Protein Information: | sulfotransferase family cytosolic 2B member 1; ST2B1; sulfotransferase 2B1; alcohol sulfotransferase; hydroxysteroid sulfotransferase 2 |
UniProt Protein Name: | Sulfotransferase family cytosolic 2B member 1 |
UniProt Synonym Protein Names: | Alcohol sulfotransferase; Hydroxysteroid sulfotransferase 2 |
Protein Family: | Sulfotransferase family cytosolic |
UniProt Gene Name: | SULT2B1 |
UniProt Entry Name: | ST2B1_HUMAN |