Anti-SEMA4D Antibody (CAB10136)
- SKU:
- CAB10136
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Developmental Biology
Description
抗体名: | Anti-SEMA4D Antibody |
抗体コード: | CAB10136 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 753-862 of human SEMA4D (NP_006369.3). |
申し込み: | WB |
推奨希釈: | WB 1:200 - 1:1000 |
反応性: | Human |
ポジティブサンプル: | 293T |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 753-862 of human SEMA4D (NP_006369.3). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | YNCY KGYL PRQC LKFR SALL IGKK KPKS DFCD REQS LKET LVEP GSFS QQNG EHPK PALD TGYE TEQD TITS KVPT DRED SQRI DDLS ARDK PFDV KCEL KFAD SDAD GD |
遺伝子ID: | 10507 |
Uniprot: | Q92854 |
セルラーロケーション: | Cell membrane, Single-pass type I membrane protein |
計算された分子量: | 82kDa/96kDa |
観察された分子量: | 150kDa |
同義語: | SEMA4D, C9orf164, CD100, M-sema-G, SEMAJ, coll-4 |
バックグラウンド: |
UniProt Protein Function: | SEMA4D: a single-pass type I membrane protein that my play a functional role in the immune system, as well as in the nervous system. Induces B-cells to aggregate and improves their viability in vitro. |
UniProt Protein Details: | Protein type:Membrane protein, integral Chromosomal Location of Human Ortholog: 9q22.2 Cellular Component: extracellular space; integral to plasma membrane; plasma membrane Molecular Function:chemorepellent activity; protein binding; receptor activity; receptor binding; semaphorin receptor binding; transmembrane receptor activity Biological Process: axon guidance; cell adhesion; immune response; negative chemotaxis; negative regulation of apoptosis; negative regulation of axon extension involved in axon guidance; negative regulation of cell adhesion; negative regulation of osteoblast differentiation; negative regulation of peptidyl-tyrosine phosphorylation; negative regulation of transcription from RNA polymerase II promoter; neural crest cell migration; positive regulation of cell migration; positive regulation of collateral sprouting; positive regulation of GTPase activity; positive regulation of peptidyl-tyrosine phosphorylation; positive regulation of phosphoinositide 3-kinase cascade; positive regulation of protein amino acid phosphorylation; regulation of cell projection organization and biogenesis; regulation of cell shape; regulation of dendrite morphogenesis |
UniProt Code: | Q92854 |
NCBI GenInfo Identifier: | 8134701 |
NCBI Gene ID: | 10507 |
NCBI Accession: | Q92854.1 |
UniProt Secondary Accession: | Q92854,Q7Z5S4, Q8N8B0, B2RPM6, |
UniProt Related Accession: | Q92854 |
Molecular Weight: | 82,164 Da |
NCBI Full Name: | Semaphorin-4D |
NCBI Synonym Full Names: | semaphorin 4D |
NCBI Official Symbol: | SEMA4D |
NCBI Official Synonym Symbols: | CD100; SEMAJ; coll-4; C9orf164; M-sema-G |
NCBI Protein Information: | semaphorin-4D |
UniProt Protein Name: | Semaphorin-4D |
UniProt Synonym Protein Names: | A8; BB18; GR3; CD_antigen: CD100 |
Protein Family: | Semaphorin |
UniProt Gene Name: | SEMA4D |
UniProt Entry Name: | SEM4D_HUMAN |