Anti-Phospho-GYS1 (S641) Antibody (RACO0054)
- SKU:
- RACO0054
- Product type:
- Recombinant Antibody
- Reactivity:
- Human
- Host Species:
- Human
- Isotype:
- IgG
- Application:
- WB
- Application:
- IF
- Application:
- ELISA
- Conjugation:
- Unconjugated
Frequently bought together:
Description
商品名: | Phospho-GYS1 (S641) Antibody |
Product SKU: | RACO0054 |
サイズ: | 50ul |
宿主種: | Human |
申し込み: | ELISA, WB, IF |
推奨される希釈: | WB:1:500-1:5000, IF:1:20-1:200 |
反応性: | Human |
免疫原: | A synthesized peptide derived from human Phospho-GYS1 (S641) |
憲法: | Liquid |
ストレージバッファ: | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
精製方法: | Affinity-chromatography |
抗体のクローン性: | Monoclonal |
アイソタイプ: | Rabbit IgG |
Conjugate: | Non-conjugated |
バックグラウンド: | Transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan. |
シノニム: | Glycogen [starch] synthase, muscle, GYS1, GYS |
Immunofluorescence staining of HepG2 cells with RACO0054 at 1:100,counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG (H+L). | |
Western Blot. Positive WB detected in Hela whole cell lysate HepG2 whole cell lysate treated with Calyculin A or EGF). All lanes Phospho-GYS1 antibody at 1.(2µg)ml. Secondary. Goat polyclonal to rabbit IgG at 1:50000 dilution. Predicted band size: 85 KDa. Observed band size: 85 KDa. |
UniProt Protein Function: | GYS1: muscle glycogen synthase 1. Transfers glucosyl residue from UDP-glucose to glycogen. Regulated allosterically by glucose-6-phosphate, and by PKA-mediated phosphorylation. |
UniProt Protein Details: | Protein type:Carbohydrate Metabolism - starch and sucrose; EC 2.4.1.11; Transferase Chromosomal Location of Human Ortholog: 19q13.3 Cellular Component: membrane; cytoplasm; inclusion body; cytosol Molecular Function:protein binding; glycogen (starch) synthase activity; protein kinase binding; glucose binding Biological Process: glycogen biosynthetic process; heart development; carbohydrate metabolic process; glucose metabolic process; pathogenesis Disease: Glycogen Storage Disease 0, Muscle |
NCBI Summary: | The protein encoded by this gene catalyzes the addition of glucose monomers to the growing glycogen molecule through the formation of alpha-1,4-glycoside linkages. Mutations in this gene are associated with muscle glycogen storage disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009] |
UniProt Code: | P13807 |
NCBI GenInfo Identifier: | 1351366 |
NCBI Gene ID: | 2997 |
NCBI Accession: | P13807.2 |
UniProt Secondary Accession: | P13807,Q9BTT9, |
UniProt Related Accession: | P13807 |
Molecular Weight: | 737 |
NCBI Full Name: | Glycogen |
NCBI Synonym Full Names: | glycogen synthase 1 (muscle) |
NCBI Official Symbol: | GYS1 |
NCBI Official Synonym Symbols: | GSY; GYS |
NCBI Protein Information: | glycogen [starch] synthase, muscle; glycogen [starch] synthase, muscle |
UniProt Protein Name: | Glycogen [starch] synthase, muscle |
Protein Family: | Glycogen [starch] synthase |
UniProt Gene Name: | GYS1 |
UniProt Entry Name: | GYS1_HUMAN |