Anti-GYS1 Antibody (CAB2519)
- SKU:
- CAB2519
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Metabolism
Frequently bought together:
Description
抗体名: | Anti-GYS1 Antibody |
抗体コード: | CAB2519 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IHC IF |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 488-737 of human GYS1 (NP_002094.2). |
申し込み: | WB IHC IF |
推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:100 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | HeLa, 293T, BT-474, Mouse heart |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 488-737 of human GYS1 (NP_002094.2). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | LLPV DYEE FVRG CHLG VFPS YYEP WGYT PAEC TVMG IPSI STNL SGFG CFME EHIA DPSA YGIY ILDR RFRS LDDS CSQL TSFL YSFC QQSR RQRI IQRN RTER LSDL LDWK YLGR YYMS ARHM ALSK AFPE HFTY EPNE ADAA QGYR YPRP ASVP PSPS LSRH SSPH QSED EEDP RNGP LEED GERY DEDE EAAK DRRN IRAP EWPR RASC TSST SGSK RNSV DTAT SSSL STPS EPLS PTSS LGEE RN |
遺伝子ID: | 2997 |
Uniprot: | P13807 |
セルラーロケーション: | |
計算された分子量: | 76kDa/83kDa |
観察された分子量: | 100kDa |
同義語: | GYS1, GSY, GYS |
バックグラウンド: | The protein encoded by this gene catalyzes the addition of glucose monomers to the growing glycogen molecule through the formation of alpha-1, 4-glycoside linkages. Mutations in this gene are associated with muscle glycogen storage disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
UniProt Protein Function: | GYS1: muscle glycogen synthase 1. Transfers glucosyl residue from UDP-glucose to glycogen. Regulated allosterically by glucose-6-phosphate, and by PKA-mediated phosphorylation. |
UniProt Protein Details: | Protein type:Carbohydrate Metabolism - starch and sucrose; EC 2.4.1.11; Transferase Chromosomal Location of Human Ortholog: 19q13.3 Cellular Component: membrane; cytoplasm; inclusion body; cytosol Molecular Function:protein binding; glycogen (starch) synthase activity; protein kinase binding; glucose binding Biological Process: glycogen biosynthetic process; heart development; carbohydrate metabolic process; glucose metabolic process; pathogenesis Disease: Glycogen Storage Disease 0, Muscle |
NCBI Summary: | The protein encoded by this gene catalyzes the addition of glucose monomers to the growing glycogen molecule through the formation of alpha-1,4-glycoside linkages. Mutations in this gene are associated with muscle glycogen storage disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009] |
UniProt Code: | P13807 |
NCBI GenInfo Identifier: | 1351366 |
NCBI Gene ID: | 2997 |
NCBI Accession: | P13807.2 |
UniProt Secondary Accession: | P13807,Q9BTT9, |
UniProt Related Accession: | P13807 |
Molecular Weight: | 737 |
NCBI Full Name: | Glycogen |
NCBI Synonym Full Names: | glycogen synthase 1 (muscle) |
NCBI Official Symbol: | GYS1 |
NCBI Official Synonym Symbols: | GSY; GYS |
NCBI Protein Information: | glycogen [starch] synthase, muscle; glycogen [starch] synthase, muscle |
UniProt Protein Name: | Glycogen [starch] synthase, muscle |
Protein Family: | Glycogen [starch] synthase |
UniProt Gene Name: | GYS1 |
UniProt Entry Name: | GYS1_HUMAN |
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