Phospho-GYS1 (Ser645) Antibody (PACO24034)
- SKU:
- PACO24034
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | Phospho-GYS1 (Ser645) Antibody (PACO24034) |
抗体コード: | PACO24034 |
サイズ: | 100ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB |
推奨される希釈: | ELISA:1:2000-1:10000, WB:1:500-1:1000 |
反応性: | Human, Mouse, Rat |
免疫原: | Peptide sequence around phosphorylation site of serine 645 (P-P-S(p)-P-S) derived from Glycogen Synthase. |
憲法: | Liquid |
ストレージバッファ: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
精製方法: | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
Western blot analysis of extracts from NIH-3T3 cells treated with PMA using Phospho-Glycogen Synthase (Ser645) antibody.The lane on the right is treated with the antigen-specific peptide. |
バックグラウンド: | Transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan. |
シノニム: | glycogen [starch] synthase; glycogen synthase; GYS; |
UniProt Protein Function: | GYS1: muscle glycogen synthase 1. Transfers glucosyl residue from UDP-glucose to glycogen. Regulated allosterically by glucose-6-phosphate, and by PKA-mediated phosphorylation. |
UniProt Protein Details: | Protein type:Carbohydrate Metabolism - starch and sucrose; EC 2.4.1.11; Transferase Chromosomal Location of Human Ortholog: 19q13.3 Cellular Component: membrane; cytoplasm; inclusion body; cytosol Molecular Function:protein binding; glycogen (starch) synthase activity; protein kinase binding; glucose binding Biological Process: glycogen biosynthetic process; heart development; carbohydrate metabolic process; glucose metabolic process; pathogenesis Disease: Glycogen Storage Disease 0, Muscle |
NCBI Summary: | The protein encoded by this gene catalyzes the addition of glucose monomers to the growing glycogen molecule through the formation of alpha-1,4-glycoside linkages. Mutations in this gene are associated with muscle glycogen storage disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009] |
UniProt Code: | P13807 |
NCBI GenInfo Identifier: | 1351366 |
NCBI Gene ID: | 2997 |
NCBI Accession: | P13807.2 |
UniProt Secondary Accession: | P13807,Q9BTT9, |
UniProt Related Accession: | P13807 |
Molecular Weight: | 737 |
NCBI Full Name: | Glycogen |
NCBI Synonym Full Names: | glycogen synthase 1 (muscle) |
NCBI Official Symbol: | GYS1 |
NCBI Official Synonym Symbols: | GSY; GYS |
NCBI Protein Information: | glycogen [starch] synthase, muscle; glycogen [starch] synthase, muscle |
UniProt Protein Name: | Glycogen [starch] synthase, muscle |
Protein Family: | Glycogen [starch] synthase |
UniProt Gene Name: | GYS1 |
UniProt Entry Name: | GYS1_HUMAN |
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