Anti-PHB2 Antibody (CAB9144)
- SKU:
- CAB9144
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Monoclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
抗体名: | Anti-PHB2 Antibody |
抗体コード: | CAB9144 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IHC IF |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | A synthesized peptide derived from human PHB2 |
申し込み: | WB IHC IF |
推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | HeLa, SKOV3, HT-1080, NIH/3T3, C6, Mouse liver, Mouse heart |
免疫原: | A synthesized peptide derived from human PHB2 |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | Email for sequence |
遺伝子ID: | 11331 |
Uniprot: | Q99623 |
セルラーロケーション: | Cytoplasm, Mitochondrion inner membrane, Nucleus |
計算された分子量: | 30kDa |
観察された分子量: | 33KDa |
同義語: | BAP, BCAP37, Bap37, PNAS-141, REA, hBAP, p22, PHB2 |
バックグラウンド: |
UniProt Protein Function: | BAP37: a protein of the band 7 family. This family includes the prohibitins, cytoplasmic anti-proliferative proteins and stomatin, an erythrocyte membrane protein. A repressor of estrogen receptor (ER) activity. Reverses steroid receptor coactivator 1 enhancement of ER activity. May play a role in determining the sensitivity of estrogen target cells to antiestrogen and estrogen therapy. |
UniProt Protein Details: | Protein type:Mitochondrial; Nuclear receptor co-regulator; Transcription, coactivator/corepressor Chromosomal Location of Human Ortholog: 12p13 Cellular Component: protein complex; nuclear matrix; mitochondrion; mitochondrial inner membrane; nucleus Molecular Function:protein binding; estrogen receptor binding Biological Process: transcription, DNA-dependent; negative regulation of transcription, DNA-dependent; negative regulation of mammary gland epithelial cell proliferation; negative regulation of estrogen receptor signaling pathway |
UniProt Code: | Q99623 |
NCBI GenInfo Identifier: | 74752151 |
NCBI Gene ID: | |
NCBI Accession: | Q99623.2 |
Molecular Weight: | |
NCBI Full Name: | Prohibitin-2 |
UniProt Protein Name: | Prohibitin-2 |
UniProt Synonym Protein Names: | B-cell receptor-associated protein BAP37; D-prohibitin; Repressor of estrogen receptor activity |
Protein Family: | Readthrough protein |
UniProt Gene Name: | PHB2 |
UniProt Entry Name: | PHB2_HUMAN |
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