Anti-PHB2 Antibody (CAB4504)
- SKU:
- CAB4504
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
抗体名: | Anti-PHB2 Antibody |
抗体コード: | CAB4504 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IHC IF |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-299 of human PHB2 (NP_001138303.1). |
申し込み: | WB IHC IF |
推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:100 IF 1:50 - 1:100 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | BT-474, 22Rv1, 293T, HepG2, A-549, Mouse heart, Mouse liver, Rat heart, Rat liver |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-299 of human PHB2 (NP_001138303.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | MAQN LKDL AGRL PAGP RGMG TALK LLLG AGAV AYGV RESV FTVE GGHR AIFF NRIG GVQQ DTIL AEGL HFRI PWFQ YPII YDIR ARPR KISS PTGS KDLQ MVNI SLRV LSRP NAQE LPSM YQRL GLDY EERV LPSI VNEV LKSV VAKF NASQ LITQ RAQV SLLI RREL TERA KDFS LILD DVAI TELS FSRE YTAA VEAK QVAQ QEAQ RAQF LVEK AKQE QRQK IVQA EGEA EAAK MLGE ALSK NPGY IKLR KIRA AQNI SKTI ATSQ NRIY LTAD NLVL NLQD ESFT RGSD SLIK GKK |
遺伝子ID: | 11331 |
Uniprot: | Q99623 |
セルラーロケーション: | Cytoplasm, Mitochondrion inner membrane, Nucleus |
計算された分子量: | 29kDa/33kDa |
観察された分子量: | 32kDa |
同義語: | PHB2, BAP, BCAP37, Bap37, PNAS-141, REA, hBAP, p22 |
バックグラウンド: |
UniProt Protein Function: | BAP37: a protein of the band 7 family. This family includes the prohibitins, cytoplasmic anti-proliferative proteins and stomatin, an erythrocyte membrane protein. A repressor of estrogen receptor (ER) activity. Reverses steroid receptor coactivator 1 enhancement of ER activity. May play a role in determining the sensitivity of estrogen target cells to antiestrogen and estrogen therapy. |
UniProt Protein Details: | Protein type:Mitochondrial; Nuclear receptor co-regulator; Transcription, coactivator/corepressor Chromosomal Location of Human Ortholog: 12p13 Cellular Component: protein complex; nuclear matrix; mitochondrion; mitochondrial inner membrane; nucleus Molecular Function:protein binding; estrogen receptor binding Biological Process: transcription, DNA-dependent; negative regulation of transcription, DNA-dependent; negative regulation of mammary gland epithelial cell proliferation; negative regulation of estrogen receptor signaling pathway |
UniProt Code: | Q99623 |
NCBI GenInfo Identifier: | 74752151 |
NCBI Gene ID: | |
NCBI Accession: | Q99623.2 |
Molecular Weight: | |
NCBI Full Name: | Prohibitin-2 |
UniProt Protein Name: | Prohibitin-2 |
UniProt Synonym Protein Names: | B-cell receptor-associated protein BAP37; D-prohibitin; Repressor of estrogen receptor activity |
Protein Family: | Readthrough protein |
UniProt Gene Name: | PHB2 |
UniProt Entry Name: | PHB2_HUMAN |
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