Anti-NRP2 Antibody (CAB12758)
- SKU:
- CAB12758
- Product type:
- Antibody
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Developmental Biology
Frequently bought together:
Description
抗体名: | Anti-NRP2 Antibody |
抗体コード: | CAB12758 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 443-740 of human NRP2 (NP_003863.2). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Mouse, Rat |
ポジティブサンプル: | Mouse kidney, Rat kidney |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 443-740 of human NRP2 (NP_003863.2). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | GLIA DSQI SASS TQEY LWSP SAAR LVSS RSGW FPRI PQAQ PGEE WLQV DLGT PKTV KGVI IQGA RGGD SITA VEAR AFVR KFKV SYSL NGKD WEYI QDPR TQQP KLFE GNMH YDTP DIRR FDPI PAQY VRVY PERW SPAG IGMR LEVL GCDW TDSK PTVE TLGP TVKS EETT TPYP TEEE ATEC GENC SFED DKDL QLPS GFNC NFDF LEEP CGWM YDHA KWLR TTWA SSSS PNDR TFPD DRNF LRLQ SDSQ REGQ YARL ISPP VHLP RSPV CMEF QYQA TGGR GVAL QVVR EASQ ES |
遺伝子ID: | 8828 |
Uniprot: | O60462 |
セルラーロケーション: | Membrane, Secreted, Single-pass type I membrane protein |
計算された分子量: | 62kDa/101kDa/102kDa/104kDa |
観察された分子量: | 95kDa |
同義語: | NRP2, NP2, NPN2, PRO2714, VEGF165R2, neuropilin-2 |
バックグラウンド: | This gene encodes a member of the neuropilin family of receptor proteins. The encoded transmembrane protein binds to SEMA3C protein {sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C} and SEMA3F protein {sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F}, and interacts with vascular endothelial growth factor (VEGF). This protein may play a role in cardiovascular development, axon guidance, and tumorigenesis. Multiple transcript variants encoding distinct isoforms have been identified for this gene. |
UniProt Protein Function: | NRP2: High affinity receptor for semaphorins 3C, 3F, VEGF-165 and VEGF-145 isoforms of VEGF, and the PLGF-2 isoform of PGF. Heterodimer with NRP1. Binds PLXNB1. Belongs to the neuropilin family. 5 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Membrane protein, integral; Receptor, misc.; Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 2q33.3 Cellular Component: extracellular region; integral to membrane; membrane; plasma membrane Molecular Function:cytokine binding; growth factor binding; heparin binding; metal ion binding; receptor activity; semaphorin receptor activity; vascular endothelial growth factor receptor activity Biological Process: angiogenesis; axon extension involved in axon guidance; axon guidance; cell adhesion; nerve development; positive regulation of endothelial cell proliferation; vascular endothelial growth factor receptor signaling pathway |
NCBI Summary: | This gene encodes a member of the neuropilin family of receptor proteins. The encoded transmembrane protein binds to SEMA3C protein {sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C} and SEMA3F protein {sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F}, and interacts with vascular endothelial growth factor (VEGF). This protein may play a role in cardiovascular development, axon guidance, and tumorigenesis. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008] |
UniProt Code: | O60462 |
NCBI GenInfo Identifier: | 215274096 |
NCBI Gene ID: | 8828 |
NCBI Accession: | O60462.2 |
UniProt Secondary Accession: | O60462,O14820, O14821, Q53TQ4, Q53TS3, Q7LBX7, Q9H2D4 Q9H2D5, Q9H2E2, Q9H2E3, Q9H2E4, E9PF66, |
UniProt Related Accession: | O60462 |
Molecular Weight: | 62,458 Da |
NCBI Full Name: | Neuropilin-2 |
NCBI Synonym Full Names: | neuropilin 2 |
NCBI Official Symbol: | NRP2 |
NCBI Official Synonym Symbols: | NP2; NPN2; PRO2714; VEGF165R2 |
NCBI Protein Information: | neuropilin-2 |
UniProt Protein Name: | Neuropilin-2 |
UniProt Synonym Protein Names: | Vascular endothelial cell growth factor 165 receptor 2 |
Protein Family: | Neuropilin |
UniProt Gene Name: | NRP2 |
UniProt Entry Name: | NRP2_HUMAN |
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