Anti-NFAT5 Antibody (CAB16649)
- SKU:
- CAB16649
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
抗体名: | Anti-NFAT5 Antibody |
抗体コード: | CAB16649 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human |
宿主種: | Rabbit |
免疫原: | A synthetic peptide corresponding to a sequence within amino acids 1300 to the C-terminus of human NFAT5 (NP_619728.2). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human |
ポジティブサンプル: | SH-SY5Y, A-549 |
免疫原: | A synthetic peptide corresponding to a sequence within amino acids 1300 to the C-terminus of human NFAT5 (NP_619728.2). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | LSPA SMSA LQTS INQQ DMQQ SPLY SPQN NMPG IQGA TSSP QPQA TLFH NTAG GTMN QLQN SPGS SQQT SGMF LFGI QNNC SQLL TSGP ATLP DQLM AISQ PGQP QNEG QPPV TTLL SQQM PENS PLAS SINT NQNI EKID LLVS LQNQ GNNL TGSF |
遺伝子ID: | 10725 |
Uniprot: | O94916 |
セルラーロケーション: | |
計算された分子量: | 10kDa/157kDa/165kDa/167kDa |
観察された分子量: | 174kDa |
同義語: | NFAT5, NF-AT5, NFATL1, NFATZ, OREBP, TONEBP |
バックグラウンド: | The product of this gene is a member of the nuclear factors of activated T cells family of transcription factors. Proteins belonging to this family play a central role in inducible gene transcription during the immune response. This protein regulates gene expression induced by osmotic stress in mammalian cells. Unlike monomeric members of this protein family, this protein exists as a homodimer and forms stable dimers with DNA elements. Multiple transcript variants encoding different isoforms have been found for this gene. |
UniProt Protein Function: | Transcription factor involved in the transcriptional regulation of osmoprotective and inflammatory genes. Regulates hypertonicity-induced cellular accumulation of osmolytes. |
NCBI Summary: | The product of this gene is a member of the nuclear factors of activated T cells family of transcription factors. Proteins belonging to this family play a central role in inducible gene transcription during the immune response. This protein regulates gene expression induced by osmotic stress in mammalian cells. Unlike monomeric members of this protein family, this protein exists as a homodimer and forms stable dimers with DNA elements. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
UniProt Code: | O94916 |
NCBI GenInfo Identifier: | 9087151 |
NCBI Gene ID: | 10725 |
NCBI Accession: | O94916.1 |
UniProt Secondary Accession: | O94916,O95693, Q7LA65, Q969Q8, Q96QH3, Q9UN18, A2RRB4 A6H8V5, E9PHR7, |
UniProt Related Accession: | O94916 |
Molecular Weight: | 167,808 Da |
NCBI Full Name: | Nuclear factor of activated T-cells 5 |
NCBI Synonym Full Names: | nuclear factor of activated T-cells 5, tonicity-responsive |
NCBI Official Symbol: | NFAT5 |
NCBI Official Synonym Symbols: | NFATZ; OREBP; NF-AT5; NFATL1; TONEBP |
NCBI Protein Information: | nuclear factor of activated T-cells 5 |
UniProt Protein Name: | Nuclear factor of activated T-cells 5 |
UniProt Synonym Protein Names: | T-cell transcription factor NFAT5; Tonicity-responsive enhancer-binding protein; TonE-binding protein; TonEBP |
Protein Family: | Nuclear factor of activated T-cells |
UniProt Gene Name: | NFAT5 |
UniProt Entry Name: | NFAT5_HUMAN |
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