Anti-NAPRT Antibody (CAB11591)
- SKU:
- CAB11591
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
抗体名: | Anti-NAPRT Antibody |
抗体コード: | CAB11591 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 309-538 of human NAPRT1 (NP_660202.3). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | HepG2, HT-29 |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 309-538 of human NAPRT1 (NP_660202.3). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | ELGY RAVG VRLD SGDL LQQA QEIR KVFR AAAA QFQV PWLE SVLI VVSN NIDE EALA RLAQ EGSE VNVI GIGT SVVT CPQQ PSLG GVYK LVAV GGQP RMKL TEDP EKQT LPGS KAAF RLLG SDGS PLMD MLQL AEEP VPQA GQEL RVWP PGAQ EPCT VRPA QVEP LLRL CLQQ GQLC EPLP SLAE SRAL AQLS LSRL SPEH RRLR SPAQ YQVV LSER LQAL VNSL CAGQ SP |
遺伝子ID: | 93100 |
Uniprot: | Q6XQN6 |
セルラーロケーション: | Cytoplasm, cytosol |
計算された分子量: | 56kDa/57kDa/60kDa |
観察された分子量: | 55kDa |
同義語: | NAPRT, NAPRT1, PP3856 |
バックグラウンド: |
UniProt Protein Function: | NAPRT1: Catalyzes the conversion of nicotinic acid (NA) to NA mononucleotide (NaMN). Essential for NA to increase cellular NAD levels and prevent oxidative stress of the cells. Belongs to the NAPRTase family. 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:EC 6.3.4.21; Transferase Chromosomal Location of Human Ortholog: 8q24.3 Cellular Component: cytosol; extracellular region Molecular Function:nicotinate phosphoribosyltransferase activity; protein binding Biological Process: neutrophil degranulation; response to oxidative stress |
NCBI Summary: | Nicotinic acid (NA; niacin) is converted by nicotinic acid phosphoribosyltransferase (NAPRT; EC 2.4.2.11) to NA mononucleotide (NaMN), which is then converted to NA adenine dinucleotide (NaAD), and finally to nicotinamide adenine dinucleotide (NAD), which serves as a coenzyme in cellular redox reactions and is an essential component of a variety of processes in cellular metabolism including response to stress (Hara et al., 2007).[supplied by OMIM, Mar 2008] |
UniProt Code: | Q6XQN6 |
NCBI GenInfo Identifier: | 166221824 |
NCBI Gene ID: | 93100 |
NCBI Accession: | Q6XQN6.2 |
UniProt Secondary Accession: | Q6XQN6,Q6PJL1, Q6XQN4, Q6XQN5, Q8N5E8, Q9BRG0, A7BFI3 |
UniProt Related Accession: | Q6XQN6 |
Molecular Weight: | 58kDa |
NCBI Full Name: | Nicotinate phosphoribosyltransferase |
NCBI Synonym Full Names: | nicotinate phosphoribosyltransferase |
NCBI Official Symbol: | NAPRT |
NCBI Official Synonym Symbols: | NAPRT1; PP3856 |
NCBI Protein Information: | nicotinate phosphoribosyltransferase |
UniProt Protein Name: | Nicotinate phosphoribosyltransferase |
UniProt Synonym Protein Names: | FHA-HIT-interacting protein; Nicotinate phosphoribosyltransferase domain-containing protein 1 |
UniProt Gene Name: | NAPRT |
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